PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35122251-0	2022	Diet-derived ergothioneine induces necroptosis in colorectal cancer cells by activating the SIRT3/MLKL pathway.	Ergothioneine	13-26	sirtuin 3	Homo sapiens	92-97	
35122251-3	2022	Egt treatment exerted cytotoxicity in a dose-dependent manner, induced reactive oxygen species accumulation, loss of mitochondrial membrane potential, and upregulation of the histone deacetylase SIRT3.	Ergothioneine	0-3	sirtuin 3	Homo sapiens	195-200	
35122251-7	2022	The SIRT3-MLKL interaction may mediate the necroptotic effects of Egt in CRC, suggesting the potential of this dietary amino-thione in the prevention of CRC.	Ergothioneine	66-69	sirtuin 3	Homo sapiens	4-9