PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16892730-1 2006 The objective of this project was to study the effect of the presence of co-solvents with dichloromethane on the properties of leu-enkephalin microcapsules. Methylene Chloride 90-105 prodynorphin Homo sapiens 127-141 6832887-4 1983 The 4-chloromethylphenoxyacetyl polystyrene resin was tested by the synthesis of Leu-enkephalin which was cleaved, at the end of the synthesis, from the solid support in 91% yield by 60% trifluoroacetic acid in methylene chloride, and was shown to be more than 99% pure by ion-exchange chromatography and reverse phase high pressure liquid chromatography. Methylene Chloride 211-229 prodynorphin Homo sapiens 81-95 12005482-5 2002 Cleavage studies of Leu-enkephalin anchored to either o-BAL or p-BAL handles revealed that both handles were surprisingly acid-labile and released the peptide with dilute TFA (5% and even 1% TFA in CH2Cl2). Methylene Chloride 198-204 prodynorphin Homo sapiens 20-34