PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32957145-2	2020	In initial investigations, the dichloromethane extract from the aerial parts of S. orientalis showed distinct inhibitory effects on the release of interleukin-8 in human neutrophils.	Methylene Chloride	31-46	C-X-C motif chemokine ligand 8	Homo sapiens	147-160	
34280354-5	2021	In addition, the expression of various genes involved in carcinogenesis, namely, NFE2L2 (antioxidative response), CXCL8 (inflammation), CDH1 (cell adhesion), MMP9 (tissue remodeling) and MKI67 (cell proliferation) were altered in cholangiocytes treated with DCM.	Methylene Chloride	258-261	C-X-C motif chemokine ligand 8	Homo sapiens	114-119	
34280354-7	2021	In malignant cell lines (HuCCA-1 and RMCCA-1), DCM treatment resulted in increased CXCL8 and MMP9 transcription and decreased CDH1 transcription accompanied by increased invasion and migration capabilities of these cells.	Methylene Chloride	47-50	C-X-C motif chemokine ligand 8	Homo sapiens	83-88	
32595508-4	2020	A dichloromethane extract (OS1), mainly composed of isoflavonoids and triterpenes as characterized by LC-MS, showed a concentration-dependent (25-100 mug/ml) inhibition of IL-8 and TNF-alpha release from LPS-stimulated human neutrophils.	Methylene Chloride	2-17	C-X-C motif chemokine ligand 8	Homo sapiens	172-176	
30193010-1	2018	In an initial screening, the dichloromethane extract from the leaves of Melodorum fruticosum showed distinct inhibitory effects on the release of interleukin-8 (IL-8) in human neutrophils.	Methylene Chloride	29-44	C-X-C motif chemokine ligand 8	Homo sapiens	161-165