PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21111586-0 2011 A methylene chloride fraction of Saururus chinensis induces apoptosis through the activation of caspase-3 in prostate and breast cancer cells. Methylene Chloride 2-20 caspase 3 Homo sapiens 96-105 24088696-5 2013 Investigations for the possible mechanism underlying the induction of apoptosis showed that CH2Cl2 fraction or compound 7 induced apoptosis through down-regulation of Bcl-2, up-regulation of Bax, cleavage of caspase-9, cleavage of caspase-3 and cleavage of poly(ADP-ribose) polymerase (PARP) in HL-60 cells. Methylene Chloride 92-98 caspase 3 Homo sapiens 231-240 32180460-10 2020 After 24 h, we found increased levels of caspase-3 activation in cells treated with 25 mug/ml dichloromethane and hexane extracts compared to untreated cells. Methylene Chloride 94-109 caspase 3 Homo sapiens 41-50