PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16317058-8	2006	In addition, DHT inhibited mRNA expression of IL-6, MCP-1, CD40, TLR4, PAI-1, and Cox-2 and the release of cytokines and chemokines such as GRO, granulocyte-macrophage colony-stimulating factor, and TNF.	Dihydrotestosterone	13-16	C-C motif chemokine ligand 2	Homo sapiens	52-57	
32755990-11	2020	DHT pre-treatment significantly decreased IFNgamma-induced expression of HLA-DR, mRNA expression of iNOS, COX2 and MCP1, and secretion of IL1, IL2, IL5, IL6, MCP1 and GCSF.	Dihydrotestosterone	0-3	C-C motif chemokine ligand 2	Homo sapiens	115-119	
32755990-11	2020	DHT pre-treatment significantly decreased IFNgamma-induced expression of HLA-DR, mRNA expression of iNOS, COX2 and MCP1, and secretion of IL1, IL2, IL5, IL6, MCP1 and GCSF.	Dihydrotestosterone	0-3	C-C motif chemokine ligand 2	Homo sapiens	158-162	
27392713-8	2016	Furthermore, luciferase-reporter analysis indicated that MCP-1 promoter activity was predominantly suppressed by dihydrotestosterone (DHT)-AR interactions through functional canonical nuclear factor-kappa B (NF-kappaB) sites, whereas non-canonical NF-kappaB site containing important flanking sequences exhibited minor contributions to DHT-AR transcriptional repression.	Dihydrotestosterone	113-132	C-C motif chemokine ligand 2	Homo sapiens	57-62	
27392713-8	2016	Furthermore, luciferase-reporter analysis indicated that MCP-1 promoter activity was predominantly suppressed by dihydrotestosterone (DHT)-AR interactions through functional canonical nuclear factor-kappa B (NF-kappaB) sites, whereas non-canonical NF-kappaB site containing important flanking sequences exhibited minor contributions to DHT-AR transcriptional repression.	Dihydrotestosterone	336-339	C-C motif chemokine ligand 2	Homo sapiens	57-62	
27392713-8	2016	Furthermore, luciferase-reporter analysis indicated that MCP-1 promoter activity was predominantly suppressed by dihydrotestosterone (DHT)-AR interactions through functional canonical nuclear factor-kappa B (NF-kappaB) sites, whereas non-canonical NF-kappaB site containing important flanking sequences exhibited minor contributions to DHT-AR transcriptional repression.	Dihydrotestosterone	134-137	C-C motif chemokine ligand 2	Homo sapiens	57-62	
23585426-5	2013	Dihydrotestosterone was found to induce a time-dependent (0-72 hours) and concentration-dependent (0-1 nmol/L) increase in CCL2 mRNA levels in androgen-responsive human prostate cancer cells (LNCaP).	Dihydrotestosterone	0-19	C-C motif chemokine ligand 2	Homo sapiens	123-127	
23585426-7	2013	The effect of dihydrotestosterone was mediated through an androgen receptor (AR)-dependent pathway as small inhibitor RNA against AR negated the induction of CCL2.	Dihydrotestosterone	14-33	C-C motif chemokine ligand 2	Homo sapiens	158-162	
23585426-8	2013	Although dihydrotestosterone also induced TWIST1 mRNA, an epithelial-mesenchymal transition-related factor, and purported inducer of CCL2, blocking its expression with small inhibitor RNA did not inhibit dihydrotestosterone induction of CCL2 mRNA.	Dihydrotestosterone	9-28	C-C motif chemokine ligand 2	Homo sapiens	133-137	
23585426-10	2013	Both I3C and DIM inhibited promotional effects of dihydrotestosterone on CCL2 and migration.	Dihydrotestosterone	50-69	C-C motif chemokine ligand 2	Homo sapiens	73-77