PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11878189-0	2002	Effect of 2-hydroxypropyl-beta-cyclodextrin on the solubility, stability, and pharmacological activity of the chemical delivery system of TRH analogs.	2-Hydroxypropyl-beta-cyclodextrin	10-43	thyrotropin releasing hormone	Mus musculus	138-141	
11878189-9	2002	The half-life of [Leu2]-TRH-CDS/HPBCD solid complex at 25 degrees C, 4 degrees C and -15 degrees C was about 100 days, 440 days and no detectable change in three months, respectively.	2-Hydroxypropyl-beta-cyclodextrin	32-37	thyrotropin releasing hormone	Mus musculus	24-27	
11878189-11	2002	Dimethyl sulfoxide although increased the solubility of [Leu2]-TRH-CDS in the 50% HPBCD solution by 1.3 times, significantly decreased its stability by 6.6 times.	2-Hydroxypropyl-beta-cyclodextrin	82-87	thyrotropin releasing hormone	Mus musculus	63-66	
11878189-1	2002	To improve the aqueous solubility and stability of the chemical delivery system (CDS) of the thyrotropin-releasing hormone (TRH) analogs, 2-hydroxypropyl-beta-cyclodextrin (HPBCD) has been attempted.	2-Hydroxypropyl-beta-cyclodextrin	138-171	thyrotropin releasing hormone	Mus musculus	93-122	
11878189-1	2002	To improve the aqueous solubility and stability of the chemical delivery system (CDS) of the thyrotropin-releasing hormone (TRH) analogs, 2-hydroxypropyl-beta-cyclodextrin (HPBCD) has been attempted.	2-Hydroxypropyl-beta-cyclodextrin	138-171	thyrotropin releasing hormone	Mus musculus	124-127	
11878189-7	2002	In pH 6.5 and 7.4 HPBCD solution, the degradation of CDS was mainly via acid catalyzed water addition reaction, thus, e.g. [Leu2]-TRH-CDS was more stable in pH 7.4 than in pH 6.5 aqueous solutions.	2-Hydroxypropyl-beta-cyclodextrin	18-23	thyrotropin releasing hormone	Mus musculus	130-133