PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29587349-9	2018	However, HPbetaCD monotherapy additionally increased cholesterol synthesis as indicated by a marked increase of the HMG-CoA and srebp-2 mRNA expression, probably as a result of increased hepatocellular proliferation.	2-Hydroxypropyl-beta-cyclodextrin	9-17	sterol regulatory element binding factor 2	Mus musculus	128-135	
21697390-4	2011	When injected into the CNS of the npc1(-/-) mouse, 2-hydroxypropyl-beta-cyclodextrin (HP-beta-CD), a compound known to prevent this C accumulation, diffused throughout the brain and was excreted with a t(½) of 6.5 h. This agent caused suppression of C synthesis, elevation of C esters, suppression of sterol regulatory-binding protein 2 (SREBP2) target genes, and activation of liver X receptor-controlled genes.	2-Hydroxypropyl-beta-cyclodextrin	51-84	sterol regulatory element binding factor 2	Mus musculus	345-351