PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14768938-4	2003	Because AID is capable of deaminating deoxy-cytidine (dC) to deoxy-uracil (dU), it might directly induce nicks (single strand DNA breaks) and also DNA-DSBs via a U-DNA glycosylase mediated base excision repair pathway ("DNA-substrate model").	du	75-77	activation induced cytidine deaminase	Homo sapiens	8-11	
23181381-3	2013	AID displays a mutagenic activity by catalyzing targeted deamination of deoxycytidine (dC) residues in DNA resulting in dU:dG mismatches, which are processed into point-mutations in SHM or double-strand breaks (DSBs) in CSR.	du	120-122	activation induced cytidine deaminase	Homo sapiens	0-3	
20082153-5	2010	Indeed, the sequence of the switch mu region is designed to maximize AID access to increase the abundance of clustered dU bases.	du	119-121	activation induced cytidine deaminase	Homo sapiens	69-72	
18370922-4	2008	AID activity converts several dC bases to dU bases in each S region, and the dU bases are then excised by the uracil DNA glycosylase UNG; the resulting abasic sites are nicked by apurinic/apyrimidinic endonuclease (APE).	du	42-44	activation induced cytidine deaminase	Homo sapiens	0-3	
22556412-7	2012	The inhibition of intrinsic AID enzymatic activity by Fe(2+) was specific, as shown by lack of inhibition of AID-mediated dC deamination by other bivalent metal ions, such as Zn(2+), Mn(2+), Mg(2+), or Ni(2+), and the inability of Fe(2+) to inhibit UNG-mediated dU excision.	du	262-264	activation induced cytidine deaminase	Homo sapiens	28-31	
15710654-1	2005	Activation-induced cytidine deaminase deaminates cytosine to uracil (dU) in DNA, which leads to mutations at C:G basepairs in immunoglobulin genes during somatic hypermutation.	du	69-71	activation induced cytidine deaminase	Homo sapiens	0-37	
12651944-6	2003	AID catalyzes dC --> dU deamination activity most avidly on double-stranded DNA substrates containing a small "transcription-like" single-stranded DNA bubble, suggesting a targeting mechanism for this enigmatic enzyme during somatic hypermutation.	du	24-26	activation induced cytidine deaminase	Homo sapiens	0-3	
11994423-2	2002	As AID is capable of deaminating deoxy-cytidine (dC) to deoxy-uracil (dU), it might induce nicks (single strand DNA breaks) and also DNA DSBs via a U-DNA glycosylase-mediated base excision repair pathway ("DNA-substrate model").	du	70-72	activation induced cytidine deaminase	Homo sapiens	3-6