PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10204994-9 1999 The B2 receptor antagonist, Hoe 140 (D-Arg0-[ Hyp3, Thi5, D-Tic7, Oic8]-BK) at 10(-7) M, significantly shifted to the right the IP3 response curves to BK giving apparent pKB values of 8.56, 9.79 and 8.84 for hB2-CHO, rB2-CHO and INT407 cells, respectively. thi5 52-56 bradykinin receptor B2 Homo sapiens 4-15 3661696-8 1987 On the other hand, the bradykinin-elicited increase of Ca2+ was almost completely inhibited by a novel B2-receptor antagonist, D-Arg-[Hyp3, Thi5,8, D-Phe7]-bradykinin. thi5 140-144 bradykinin receptor B2 Homo sapiens 103-114 3037391-4 1987 The B2-receptor antagonist Thi5,8, D-Phe7-BK but not the B1-receptor antagonist des-Arg9-Leu8-BK selectively blocked BK-induced relaxations of the human basilar artery. thi5 27-31 bradykinin receptor B2 Homo sapiens 4-15 7749364-7 1994 Interestingly, the mouse B2 bradykinin receptor has a 60-80 fold higher affinity than the human B2 bradykinin receptor for the peptide antagonists D-Arg0[Hyp3,Thi5,8,D-Phe7]bradykinin and D-Arg0[Hyp3,D-Phe7]bradykinin. thi5 159-163 bradykinin receptor B2 Homo sapiens 96-118 1314587-7 1992 The BK-2 receptor antagonist Hoe 140 (2), D-Arg0[Hyp3, Thi5, D-Tic7, Oic8]BK has a high affinity (IC50 = 65 pM) for the cloned human receptor. thi5 55-59 bradykinin receptor B2 Homo sapiens 4-17