PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17932766-0 2008 Captopril and lisinopril decrease acetaldehyde effects upon the prothrombin time. Lisinopril 14-24 coagulation factor II, thrombin Homo sapiens 64-75 17932766-1 2008 Captopril, a thiol-containing antihypertensive drug, and lisinopril, an amino-containing antihypertensive drug, will both prolong the prothrombin time (PT) of Level I plasma. Lisinopril 57-67 coagulation factor II, thrombin Homo sapiens 134-145 8165541-0 1994 Both lisinopril and verapamil reduced platelet-derived growth factor-A chain mRNA levels in human saphenous vein endothelial cells stimulated by thrombin. Lisinopril 5-15 coagulation factor II, thrombin Homo sapiens 145-153 8165541-6 1994 PDGF-AA homodimer in conditioned media was measured by ELISA: RESULTS: Lisinopril attenuated the induction by thrombin of PDGF-A chain mRNA levels significantly in human ECs at doses of 10(-6) mol/L and 10(-5) mol/L (p < 0.05) and appeared to decrease PDGF-AA homodimer released in conditioned medium. Lisinopril 71-81 coagulation factor II, thrombin Homo sapiens 110-118 8165541-8 1994 CONCLUSIONS: These data suggest that one means by which lisinopril and verapamil both suppress intimal thickening might be inhibition of PDGF-A chain gene expression in ECs regrowing over vessel injury areas that are sites of thrombin generation. Lisinopril 56-66 coagulation factor II, thrombin Homo sapiens 226-234 2172073-3 1990 Continuation of lisinopril administration for 3 weeks after the onset of jaundice was associated with the development of grade III encephalopathy and a marked decrease in prothrombin and proaccelerin levels. Lisinopril 16-26 coagulation factor II, thrombin Homo sapiens 171-182