PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16221218-1	2005	BACKGROUND: Angiotensin-converting enzyme (ACE)2, a homologue of ACE, which is insensitive to ACE inhibitors and forms angiotensin-(1-7) [Ang-(1-7)] from angiotensin II (Ang II) with high efficiency was investigated in response to chronic blockade with lisinopril, losartan, and both drugs combined.	Lisinopril	253-263	angiotensin I converting enzyme 2	Rattus norvegicus	43-48	
16766648-3	2006	The control of blood pressure elicited by 12-day administration of either lisinopril (mean difference change = 92 +/- 2, P < 0.05) or losartan (mean difference change = 69 +/- 2, P < 0.05) was associated with 54% and 33% increases in cardiac ACE2 mRNA and 54% and 43% increases in cardiac ACE mRNA, respectively.	Lisinopril	74-84	angiotensin I converting enzyme 2	Rattus norvegicus	242-246	
16766648-4	2006	Lisinopril induced a 3.1-fold (P < 0.05) increase in renal cortical expression of ACE2, whereas losartan increased ACE2 mRNA 3.5-fold (P < 0.05).	Lisinopril	0-10	angiotensin I converting enzyme 2	Rattus norvegicus	82-86	
16221218-13	2005	Renal cortex ACE2 activity was significantly augmented in rats medicated with lisinopril or losartan but not changed in those given the combination.	Lisinopril	78-88	angiotensin I converting enzyme 2	Rattus norvegicus	13-17