PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17884087-3 2007 Compared with the lisinopril-MMP-9 model in our previous study, imidapril was stabilized effectively on the active site with less of molecular distortions. Lisinopril 18-28 matrix metallopeptidase 9 Homo sapiens 29-34 17884087-4 2007 We also measured ACE and MMP-9 inhibitory activities of imidapril and lisinopril after myocardial infarction. Lisinopril 70-80 matrix metallopeptidase 9 Homo sapiens 25-30 17884087-6 2007 These findings show that imidapril inhibits MMP-9 directly like lisinopril and its hydrophobic interactions with the S1 site of MMP-9 would be important for enhancing inhibitory activity. Lisinopril 64-74 matrix metallopeptidase 9 Homo sapiens 44-49 17275782-1 2007 To characterize the inhibitory specificity of angiotensin converting enzyme (ACE) inhibitors for matrix metalloproteinase 9 (MMP-9) activity, molecular modeling of these complex was performed referring the recent X-ray structure analyses using lisinopril as an ACE inhibitor. Lisinopril 244-254 matrix metallopeptidase 9 Homo sapiens 97-123 17512521-0 2007 Inhibition of matrix metalloproteinase-9 activity by lisinopril after myocardial infarction in hamsters. Lisinopril 53-63 matrix metallopeptidase 9 Homo sapiens 14-40 17512521-4 2007 Lisinopril significantly inhibited both angiotensin-converting enzyme and matrix metalloproteinase-9 activities, but candesartan cilexetil did not. Lisinopril 0-10 matrix metallopeptidase 9 Homo sapiens 74-100 17275782-1 2007 To characterize the inhibitory specificity of angiotensin converting enzyme (ACE) inhibitors for matrix metalloproteinase 9 (MMP-9) activity, molecular modeling of these complex was performed referring the recent X-ray structure analyses using lisinopril as an ACE inhibitor. Lisinopril 244-254 matrix metallopeptidase 9 Homo sapiens 125-130 17275782-3 2007 Lisinopril was effectively stabilized by specific hydrogen bonds and hydrophobic interactions in the active site of MMP-9, and its hydrophobic group appeared to interact preferentially with the S1 site compared with the S1" site. Lisinopril 0-10 matrix metallopeptidase 9 Homo sapiens 116-121 12381651-8 2002 Lisinopril inhibited MMP-9 significantly but did not inhibit MMP-2 in vitro (IC50 MMP-2: 7.4 (0.88); MMP-9: 7.86 (2.23)). Lisinopril 0-10 matrix metallopeptidase 9 Homo sapiens 21-26