PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25932125-7	2015	In addition, nicorandil increased the protein levels of p-Akt and p-GSK-3beta by PI3K activation.	Nicorandil	13-23	AKT serine/threonine kinase 1	Homo sapiens	58-61	
24008440-0	2013	Effects of nicorandil in neuroprotective activation of PI3K/AKT pathways in a cellular model of Alzheimer"s disease.	Nicorandil	11-21	AKT serine/threonine kinase 1	Homo sapiens	60-63	
24008440-10	2013	Further studies showed that nicorandil increased the levels of phospho-Akt and upregulated element-binding protein activity by PI3K activation.	Nicorandil	28-38	AKT serine/threonine kinase 1	Homo sapiens	71-74	
32407984-0	2020	Nicorandil reversed homocysteine-induced coronary microvascular dysfunction via regulating PI3K/Akt/eNOS pathway.	Nicorandil	0-10	AKT serine/threonine kinase 1	Homo sapiens	96-99	
32407984-7	2020	RESULTS: The results showed that nicorandil improved cell viability and p-PI3K/PI3K, p-Akt/Akt, and p-eNOS/eNOS expression in the vitro HHcy and hypoxia models.	Nicorandil	33-43	AKT serine/threonine kinase 1	Homo sapiens	87-90	
32407984-7	2020	RESULTS: The results showed that nicorandil improved cell viability and p-PI3K/PI3K, p-Akt/Akt, and p-eNOS/eNOS expression in the vitro HHcy and hypoxia models.	Nicorandil	33-43	AKT serine/threonine kinase 1	Homo sapiens	91-94	
32407984-11	2020	CONCLUSION: The results suggest that nicorandil improves Hcy-induced coronary microvascular dysfunction through the PI3K/Akt/eNOS signalling pathway.	Nicorandil	37-47	AKT serine/threonine kinase 1	Homo sapiens	121-124	
31131539-15	2019	These results verified that as a NO donor, nicorandil can also inhibit apoptosis in diabetic cardiomyopathy which is mediated by PI3K/Akt pathway.	Nicorandil	43-53	AKT serine/threonine kinase 1	Homo sapiens	134-137