PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12153580-2	2002	With the aim to distinguish between local and global conformational changes induced by trifluoroethanol in RNase A, spectroscopic and activity measurements in combination with proteolysis by unspecific proteases have been exploited for probing structural transitions of RNase A as a function of trifluoroethanol concentration.	Trifluoroethanol	87-103	ribonuclease A family member 1, pancreatic	Homo sapiens	107-114	
12153580-2	2002	With the aim to distinguish between local and global conformational changes induced by trifluoroethanol in RNase A, spectroscopic and activity measurements in combination with proteolysis by unspecific proteases have been exploited for probing structural transitions of RNase A as a function of trifluoroethanol concentration.	Trifluoroethanol	87-103	ribonuclease A family member 1, pancreatic	Homo sapiens	270-277	
12153580-3	2002	At > 30% (v/v) trifluoroethanol (pH 8.0; 25 degrees C), circular dichroism and fluorescence spectroscopy indicate a cooperative collapse of the tertiary structure of RNase A coinciding with the loss of its enzymatic activity.	Trifluoroethanol	18-34	ribonuclease A family member 1, pancreatic	Homo sapiens	169-176	
10449045-1	1999	The effect(s) of TFE (2,2,2-trifluoroethanol) on three different conformational states (native, denatured, and carboxymethylated) of CTX III and RNase A has been examined.	Trifluoroethanol	17-20	ribonuclease A family member 1, pancreatic	Homo sapiens	145-152	
10449045-1	1999	The effect(s) of TFE (2,2,2-trifluoroethanol) on three different conformational states (native, denatured, and carboxymethylated) of CTX III and RNase A has been examined.	Trifluoroethanol	22-44	ribonuclease A family member 1, pancreatic	Homo sapiens	145-152	
18225649-4	2007	The same peptide bonds are splitted by proteases with the highest rate upon the denaturation in the presense of trifluoroethanol or the renaturation from concentrated urea solutions and after the desorganization of the native structure by the reduction of all four S-S bonds of RNase A.	Trifluoroethanol	112-128	ribonuclease A family member 1, pancreatic	Homo sapiens	278-285