PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9265617-4 1997 To characterize the putative bioactive conformation, we have carried out a detailed structural analysis of a series of three conformationally constrained PTHrP-(1-34)-based mono- and bicyclic lactam-containing biologically active analogs: (III) The conformational properties were studied by circular dichroisim, nuclear magnetic resonance spectroscopy, distance geometry calculations, and molecular dynamic simulations in water/trifluoroethanol (TFE) mixtures. Trifluoroethanol 428-444 parathyroid hormone like hormone Homo sapiens 154-159 9265617-4 1997 To characterize the putative bioactive conformation, we have carried out a detailed structural analysis of a series of three conformationally constrained PTHrP-(1-34)-based mono- and bicyclic lactam-containing biologically active analogs: (III) The conformational properties were studied by circular dichroisim, nuclear magnetic resonance spectroscopy, distance geometry calculations, and molecular dynamic simulations in water/trifluoroethanol (TFE) mixtures. Trifluoroethanol 446-449 parathyroid hormone like hormone Homo sapiens 154-159 1846369-3 1991 Circular dichroism (CD) studies of bovine PTH-(1-34) and human PTHrP-(1-34)amide in the presence of trifluoroethanol suggest the presence of 24-26 alpha-helical residues. Trifluoroethanol 100-116 parathyroid hormone like hormone Homo sapiens 63-68 7947956-1 1994 The structure of the biologically active mutant PTHrP[Ala-26](1-34)amide in 10% trifluoroethanol was studied by two-dimensional proton NMR spectroscopy. Trifluoroethanol 80-96 parathyroid hormone like hormone Homo sapiens 48-53 8138348-1 1994 The secondary structure of amino terminal fragments of human parathyroid hormone related protein (PTHrP) in aqueous solution, in trifluoroethanol solution and in the presence of model membrane systems has been studied by circular dichroism (CD) spectroscopy. Trifluoroethanol 129-145 parathyroid hormone like hormone Homo sapiens 61-96