PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24200862-8	2014	The external aldimine of kynurenine and PLP is then deprotonated by the epsilon-amino group of Lys-227 to give a quinonoid intermediate, which is reprotonated at C-4" to give a ketimine.	quinonoid	113-122	pyridoxal phosphatase	Homo sapiens	40-43	
17165790-2	2006	The present study shows that the enhancement of carbon acidity of alpha-amino acids by the cofactor pyridoxal 5"-phosphate (PLP) with an unusual, unprotonated pyridine is mainly due to solvation effects, in contrast to the intrinsic electron-withdrawing stabilization by the pyridinium ion to form a quinonoid intermediate.	quinonoid	300-309	pyridoxal phosphatase	Homo sapiens	124-127	
15560798-2	2004	To shed light on the mechanism of isotopic exchange of alpha-protons in amino acids catalyzed by pyridoxal phosphate (PLP)-dependent enzymes, we studied the kinetics of quinonoid intermediate formation for the reactions of tyrosine phenol-lyase with L-phenylalanine, L-methionine, and their alpha-deuterated analogues in D2O, and we compared the results with the rates of the isotopic exchange under the same conditions.	quinonoid	169-178	pyridoxal phosphatase	Homo sapiens	118-121	
26426567-0	2015	Mechanism-Based Trapping of the Quinonoid Intermediate by Using the K276R Mutant of PLP-Dependent 3-Aminobenzoate Synthase PctV in the Biosynthesis of Pactamycin.	quinonoid	32-41	pyridoxal phosphatase	Homo sapiens	84-87	
19346561-7	2009	Global analysis of the time-resolved spectra suggested the presence of the two quinonoid intermediates, the first formed from the PLP-l-serine aldimine and the second from the PLP-KDS aldimine.	quinonoid	79-88	pyridoxal phosphatase	Homo sapiens	130-133	
19346561-8	2009	Accumulation of these quinonoid intermediates indicated that His(159) promotes both the Claisen-type condensation as an acid catalyst and the protonation at Calpha of the second quinonoid to form the PLP-KDS aldimine.	quinonoid	22-31	pyridoxal phosphatase	Homo sapiens	200-203	
19346561-8	2009	Accumulation of these quinonoid intermediates indicated that His(159) promotes both the Claisen-type condensation as an acid catalyst and the protonation at Calpha of the second quinonoid to form the PLP-KDS aldimine.	quinonoid	178-187	pyridoxal phosphatase	Homo sapiens	200-203