PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16787057-2 2006 The present studies show that enhancement of carbon acidity of alpha-amino acids by cofactor pyridoxal 5"-phosphate, PLP, with an unusual, unprotonated pyridine is due to solvation effects, in contrast to the intrinsic electron-withdrawing stabilization by the pyridinium ion to form a quinonoid intermediate. quinonoid 286-295 proteolipid protein 1 Homo sapiens 117-120