PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1566832-3 1992 In nondiabetic (ND) rats, both ic and iv Oxo resulted in significant (P less than 0.05) rCBF increases from values obtained during saline infusions in the regions analyzed. Oxotremorine 41-44 CCAAT/enhancer binding protein zeta Rattus norvegicus 88-92 1566832-6 1992 The CBF response was associated with no change in cortical CMRO2 and was completely blocked during ic atropine-Oxo co-infusion or iv co-infusion of Oxo with the nitric oxide (NO) synthesis inhibitor L-nitroarginine methyl ester, demonstrating, respectively, no role for metabolic activation, the exclusive role of MR values, and the critical role for the release of the putative endothelium-dependent relaxation factor NO in mediating this effect. Oxotremorine 111-114 CCAAT/enhancer binding protein zeta Rattus norvegicus 4-7