PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11774366-8	2001	Thus, the addition of a pyridine ring to NPYR or NPIP altered the forms of CYP primarily responsible for mutagenic activation.	pyridine	24-32	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	75-78	
2061924-1	1991	A series of 21 different 4-substituted 2,6-dimethyl-3-(alkoxycarbonyl)-1,4-dihydropyridines was considered with regard to oxidation to pyridine derivatives by human liver microsomal cytochrome P-450 (P-450).	pyridine	82-90	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	182-198	
10805063-2	2000	It is now commonly agreed that the oxidation of 1,4-dihydropyridine into pyridine, which is one of the main metabolic pathways, is catalysed by the cytochrome P450 (CYP) 3A4 isoform.	pyridine	59-67	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	148-163	
10805063-2	2000	It is now commonly agreed that the oxidation of 1,4-dihydropyridine into pyridine, which is one of the main metabolic pathways, is catalysed by the cytochrome P450 (CYP) 3A4 isoform.	pyridine	59-67	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	165-168	
3327676-14	1987	The first step in the metabolism involves oxidation to the corresponding pyridine derivative by the cytochrome P-450 system.	pyridine	73-81	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	100-116	
182488-8	1976	This supports the model that one of the pyridine nitrogens of metyrapone is coordinated to the iron of cytochrome P-450.	pyridine	40-48	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	103-119