PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34902580-5	2022	In addition, cystathionine-gamma-lyase (CSE) inhibitor D,L-propargylglycine (PAG, 10-2 M), cystathionine-beta-synthase inhibitor (CBS) aminooxyacetic acid (AOAA, 10-2 M), and the combination of these inhibitors significantly reduced the relaxant responses induced by l-cysteine and BRL 37344.	Aminooxyacetic Acid	135-154	cystathionine beta-synthase	Mus musculus	91-118	
34902580-5	2022	In addition, cystathionine-gamma-lyase (CSE) inhibitor D,L-propargylglycine (PAG, 10-2 M), cystathionine-beta-synthase inhibitor (CBS) aminooxyacetic acid (AOAA, 10-2 M), and the combination of these inhibitors significantly reduced the relaxant responses induced by l-cysteine and BRL 37344.	Aminooxyacetic Acid	156-160	cystathionine beta-synthase	Mus musculus	91-118	
30036087-4	2019	Inhibition of both cystathionine-gamma-lyase (CSE) and cystathionine-beta-synthase (CBS), 2 major enzymes for endogenous H2S production, with propargylglycine (PPG) and amino-oxyacetate (AOAA), respectively, caused increased urine output and reduced urine osmolality in mice that was associated with decreased expression of aquaporin (AQP)-2 in the renal inner medulla.	Aminooxyacetic Acid	169-185	cystathionine beta-synthase	Mus musculus	55-82	
33271147-8	2021	During exposure to an effective CBS and CSE inhibitor (aminooxyacetic acid [AOAA]), the amplitude of oscillation and baseline expression of Per2 significantly increased.	Aminooxyacetic Acid	55-74	cystathionine beta-synthase	Mus musculus	32-35	
33271147-8	2021	During exposure to an effective CBS and CSE inhibitor (aminooxyacetic acid [AOAA]), the amplitude of oscillation and baseline expression of Per2 significantly increased.	Aminooxyacetic Acid	76-80	cystathionine beta-synthase	Mus musculus	32-35	
31349040-9	2019	Inhibition of H2S-synthesizing enzymes, cystathionine-gamma-lyase (CSE) and cystathionine-beta-synthase (CBS), by pretreating cells with propargylglycine (PAG) and oxyaminoacetic acid (AOAA) revealed that H2S production was partially dependent on a CSE/CBS-catalyzed beta-elimination reaction with CySSPe that likely produced 1-propenyl persulfide (RSSH).	Aminooxyacetic Acid	185-189	cystathionine beta-synthase	Mus musculus	76-103	
31440142-8	2019	However, H2S could not restore brain CBS expression and H2S content, reduce brain edema, and improve motor performance and memory function after ICH through modulating autophagy and apoptosis when pretreated with the CBS inhibitor aminooxyacetic acid (AOAA).	Aminooxyacetic Acid	231-250	cystathionine beta-synthase	Mus musculus	217-220	
31137614-5	2019	Amino-oxyacetic acid (AOA)-a systemic dual inhibitor of cystathionine-beta-synthase and cystathionine-gamma lyase (two key enzymes in the production of H2S)-was administered to fALS mice.	Aminooxyacetic Acid	0-20	cystathionine beta-synthase	Mus musculus	56-83	
31137614-5	2019	Amino-oxyacetic acid (AOA)-a systemic dual inhibitor of cystathionine-beta-synthase and cystathionine-gamma lyase (two key enzymes in the production of H2S)-was administered to fALS mice.	Aminooxyacetic Acid	22-25	cystathionine beta-synthase	Mus musculus	56-83	
30036087-4	2019	Inhibition of both cystathionine-gamma-lyase (CSE) and cystathionine-beta-synthase (CBS), 2 major enzymes for endogenous H2S production, with propargylglycine (PPG) and amino-oxyacetate (AOAA), respectively, caused increased urine output and reduced urine osmolality in mice that was associated with decreased expression of aquaporin (AQP)-2 in the renal inner medulla.	Aminooxyacetic Acid	169-185	cystathionine beta-synthase	Mus musculus	84-87	
30036087-4	2019	Inhibition of both cystathionine-gamma-lyase (CSE) and cystathionine-beta-synthase (CBS), 2 major enzymes for endogenous H2S production, with propargylglycine (PPG) and amino-oxyacetate (AOAA), respectively, caused increased urine output and reduced urine osmolality in mice that was associated with decreased expression of aquaporin (AQP)-2 in the renal inner medulla.	Aminooxyacetic Acid	187-191	cystathionine beta-synthase	Mus musculus	55-82	
30036087-4	2019	Inhibition of both cystathionine-gamma-lyase (CSE) and cystathionine-beta-synthase (CBS), 2 major enzymes for endogenous H2S production, with propargylglycine (PPG) and amino-oxyacetate (AOAA), respectively, caused increased urine output and reduced urine osmolality in mice that was associated with decreased expression of aquaporin (AQP)-2 in the renal inner medulla.	Aminooxyacetic Acid	187-191	cystathionine beta-synthase	Mus musculus	84-87	
23133623-13	2012	Intraperitoneal injection (i.p) of DL-propargylglycine, an irreversible inhibitor of CSE, and aminooxyacetic acid, an inhibitor of CBS, elevated the expression of TNF-alpha mRNA in the tunica muscularis of the ileum.	Aminooxyacetic Acid	94-113	cystathionine beta-synthase	Mus musculus	131-134	
25008073-4	2014	ES-induced contractions were neurotoxin-sensitive and increased by aminooxyacetic acid, an inhibitor of cystathionine beta-synthase (CBS) and cystathionine gamma-lyase, but not by D,L-propargylglycine, a selective inhibitor of cystathionine gamma-lyase, in an ES trial-dependent manner.	Aminooxyacetic Acid	67-86	cystathionine beta-synthase	Mus musculus	104-131