PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3390202-8 1988 Cytochrome b5 had no effect on CDE production by PBRLM4 and inhibited the production of both CTE and CDE by RLM2. 1,1,1-trifluoro-2-chloroethane 93-96 cytochrome b5 type A Rattus norvegicus 0-13 3689822-1 1987 To study the modulation of the reductive metabolism of halothane (2-bromo-2-chloro-1,1,1-trifluoroethane) by microsomal cytochrome b5, formation of 2-chloro-1,1,1-trifluoroethane (CTE) and 2-chloro-1,1-difluoroethylene (CDE), major reduced metabolites of halothane, was analyzed in vivo and in vitro. 1,1,1-trifluoro-2-chloroethane 74-104 cytochrome b5 type A Rattus norvegicus 120-133 3689822-7 1987 These results suggested that cytochrome b5 enhances the formation ratio of CDE to CTE by stimulating the supply of a second electron to cytochrome P-450, which might reduce radical reactions in the reductive metabolism of halothane. 1,1,1-trifluoro-2-chloroethane 82-85 cytochrome b5 type A Rattus norvegicus 29-42