PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30682092-1 2019 OBJECTIVES: This study aimed to retrospectively assess the clinical outcome with nitrofurantoin and pivmecillinam for lower urinary tract infections (UTI) in men. Nitrofurantoin 81-95 alpha-1-microglobulin/bikunin precursor Homo sapiens 150-153 482171-3 1979 A first, uncomplicated UTI should be treated with sulfonamides or nitrofurantoin. Nitrofurantoin 66-80 alpha-1-microglobulin/bikunin precursor Homo sapiens 23-26 30682092-8 2019 New prescriptions of UTI antibiotics and relapse within 3 months after completion of therapy were more frequent with nitrofurantoin (34% and 15%) and pivmecillinam (30% and 17%) than trimethoprim (22 and 7%). Nitrofurantoin 117-131 alpha-1-microglobulin/bikunin precursor Homo sapiens 21-24 27542332-1 2017 OBJECTIVES: Nitrofurantoin has been used for the prevention of urinary tract infection (UTI) for over 60 years. Nitrofurantoin 12-26 alpha-1-microglobulin/bikunin precursor Homo sapiens 88-91 29710295-1 2018 Importance: The use of nitrofurantoin and fosfomycin has increased since guidelines began recommending them as first-line therapy for lower urinary tract infection (UTI). Nitrofurantoin 23-37 alpha-1-microglobulin/bikunin precursor Homo sapiens 165-168 29710295-13 2018 Conclusions and Relevance: Among women with uncomplicated UTI, 5-day nitrofurantoin, compared with single-dose fosfomycin, resulted in a significantly greater likelihood of clinical and microbiologic resolution at 28 days after therapy completion. Nitrofurantoin 69-83 alpha-1-microglobulin/bikunin precursor Homo sapiens 58-61 27542332-3 2017 METHODS: We performed a systematic review of all controlled trials in humans assessing nitrofurantoin for UTI prophylaxis published from 1946 to 2015. Nitrofurantoin 87-101 alpha-1-microglobulin/bikunin precursor Homo sapiens 106-109 27542332-8 2017 When compared with no prophylaxis, nitrofurantoin is effective in the prevention of UTI (risk ratio 0.38 in favour of nitrofurantoin, 95% CI 0.30-0.48). Nitrofurantoin 35-49 alpha-1-microglobulin/bikunin precursor Homo sapiens 84-87 27542332-8 2017 When compared with no prophylaxis, nitrofurantoin is effective in the prevention of UTI (risk ratio 0.38 in favour of nitrofurantoin, 95% CI 0.30-0.48). Nitrofurantoin 118-132 alpha-1-microglobulin/bikunin precursor Homo sapiens 84-87 27542332-13 2017 CONCLUSIONS: Nitrofurantoin is effective in the prevention of UTI. Nitrofurantoin 13-27 alpha-1-microglobulin/bikunin precursor Homo sapiens 62-65 28486532-18 2017 In conclusion, nitrofurantoin and amoxicillin should be used as first line antibiotic treatment for uncomplicated UTI. Nitrofurantoin 15-29 alpha-1-microglobulin/bikunin precursor Homo sapiens 114-117 26454061-10 2016 In complicated UTI, ampicillin is probably a safe treatment option, whereas nitrofurantoin is probably effective in uncomplicated UTI. Nitrofurantoin 76-90 alpha-1-microglobulin/bikunin precursor Homo sapiens 130-133 26851821-2 2016 The study aim was to compare bacterial resistances to ofloxacin, cefixim, co-trimoxazole, nitrofurantoin and fosfomycin in UTI between patients with and without diabetes. Nitrofurantoin 90-104 alpha-1-microglobulin/bikunin precursor Homo sapiens 123-126 24728312-5 2014 RESULTS: The susceptibility pattern presented in this research shows that the choice for UTI treatment during pregnancy should be nitrofurantoin (for uncomplicated infections) or second-generation cephalosporins such as cefuroxime (for uncomplicated and complicated infections), over ampicillin, first-generation cephalosporins and sulfamethoxazole/trimethoprim. Nitrofurantoin 130-144 alpha-1-microglobulin/bikunin precursor Homo sapiens 89-92 26066581-1 2015 OBJECTIVES: Nitrofurantoin"s use has increased exponentially since recent guidelines repositioned it as first-line therapy for uncomplicated lower urinary tract infection (UTI). Nitrofurantoin 12-26 alpha-1-microglobulin/bikunin precursor Homo sapiens 172-175 26066581-2 2015 We conducted a systematic review and meta-analysis to assess nitrofurantoin"s efficacy and toxicity in the treatment of lower UTI. Nitrofurantoin 61-75 alpha-1-microglobulin/bikunin precursor Homo sapiens 126-129 26066581-3 2015 METHODS: We performed a systematic review of all human controlled clinical trials published from 1946 to 2014 and assessing short-term (<=14 days) nitrofurantoin for lower UTI. Nitrofurantoin 150-164 alpha-1-microglobulin/bikunin precursor Homo sapiens 175-178 26066581-6 2015 Nitrofurantoin appears to have good clinical and microbiological efficacy for UTI caused by common uropathogens, with clinical cure rates varying between 79% and 92%. Nitrofurantoin 0-14 alpha-1-microglobulin/bikunin precursor Homo sapiens 78-81 26066581-13 2015 CONCLUSIONS: When given short term for lower UTI, nitrofurantoin has good clinical and microbiological efficacy; toxicity is mild and predominantly gastrointestinal. Nitrofurantoin 50-64 alpha-1-microglobulin/bikunin precursor Homo sapiens 45-48 25935915-1 2015 Nitrofurantoin is commonly prescribed to treat urinary tract infections (UTI). Nitrofurantoin 0-14 alpha-1-microglobulin/bikunin precursor Homo sapiens 73-76 25935915-3 2015 We report a case of a 67-year-old woman treated for UTI with nitrofurantoin who presented with antineutrophilic cytoplasmic antibody (ANCA)-associated renal and skin vasculitis 3 days after starting treatment. Nitrofurantoin 61-75 alpha-1-microglobulin/bikunin precursor Homo sapiens 52-55 20172675-1 2010 AIM AND METHOD: We assessed the impact of a committed guideline at the end of the first quarter 2008 on the management of urinary tract infection (UTI) with antibiotic prescription (fluoroquinolone, fosfomycin, and nitrofurantoin), by analysing reimbursement data for ambulatory care provided by the regional health insurance agency. Nitrofurantoin 215-229 alpha-1-microglobulin/bikunin precursor Homo sapiens 147-150 15362088-5 2004 RESULTS: About 90% of E. coli causing UTI is still susceptible to nitrofurantoin, a relatively inexpensive and safe drug. Nitrofurantoin 66-80 alpha-1-microglobulin/bikunin precursor Homo sapiens 38-41 15482387-1 2004 CONTEXT: Trimethoprim-sulfamethoxazole (TMP-SMX) and nitrofurantoin were until recently the two drugs recommended in clinical guidelines in Israel for empiric treatment of uncomplicated urinary tract infection (UTI) in women. Nitrofurantoin 53-67 alpha-1-microglobulin/bikunin precursor Homo sapiens 211-214 19561661-6 2009 For lower UTI nitrofurantoin is an excellent first choice. Nitrofurantoin 14-28 alpha-1-microglobulin/bikunin precursor Homo sapiens 10-13 16445153-10 2005 Nitrofurantoin, nalidixic acid and ciprofloxacin are active against the great majority of UTI associated E. coli. Nitrofurantoin 0-14 alpha-1-microglobulin/bikunin precursor Homo sapiens 90-93 12766829-3 2003 We recorded 124 episodes of UTI in women who received estriol-releasing pessaries and 48 episodes of UTI in women treated with NM (P=.0003). Nitrofurantoin 127-129 alpha-1-microglobulin/bikunin precursor Homo sapiens 101-104 1995494-1 1991 Nitrofurantoin is one of many antibiotics used in the treatment of urinary tract infections (UTI). Nitrofurantoin 0-14 alpha-1-microglobulin/bikunin precursor Homo sapiens 93-96 7880087-5 1994 It is recommended that nitrofurantoin and nalidixic acid be used for blind treatment of UTI in Nigerian children in Ibadan while results of culture and sensitivity are awaited. Nitrofurantoin 23-37 alpha-1-microglobulin/bikunin precursor Homo sapiens 88-91 1995494-3 1991 We report a case of nitrofurantoin drug fever associated with its use, following sexual intercourse, for chemoprophylaxis of UTI. Nitrofurantoin 20-34 alpha-1-microglobulin/bikunin precursor Homo sapiens 125-128 34111584-11 2022 CONCLUSION: Daily prophylaxis for recurrent UTI with 100 mg instead of 50 mg nitrofurantoin was associated with an equivalent hazard on UTI or pyelonephritis, and a higher hazard on cough, dyspnea and nausea. Nitrofurantoin 77-91 alpha-1-microglobulin/bikunin precursor Homo sapiens 44-47 34111584-11 2022 CONCLUSION: Daily prophylaxis for recurrent UTI with 100 mg instead of 50 mg nitrofurantoin was associated with an equivalent hazard on UTI or pyelonephritis, and a higher hazard on cough, dyspnea and nausea. Nitrofurantoin 77-91 alpha-1-microglobulin/bikunin precursor Homo sapiens 136-139