PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12095984-0 2002 Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A. sanglifehrin A 0-14 peptidylprolyl isomerase D Rattus norvegicus 137-150 12095984-3 2002 Here we demonstrate that SfA inhibits the PPIase activity of CyP-D (K(0.5) 2 nm) and acts as a potent inhibitor of MPTP opening under both energized and de-energized conditions. sanglifehrin A 25-28 peptidylprolyl isomerase D Rattus norvegicus 61-66