PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16398698-0 2006 Immunosuppressive activity of the immunophilin-binding drug Sanglifehrin A in human whole blood: potent inhibition of interleukin-6 produced by lymphocytes and monocytes. sanglifehrin A 60-74 interleukin 6 Homo sapiens 118-131 16398698-11 2006 Considering the pleiotropic role of bioactive IL-6 production at the interface of innate and acquired immunity in a variety of disease conditions, it was found that these novel aspects of the unique immunosuppressive action could strongly impact on future clinical application of SFA. sanglifehrin A 280-283 interleukin 6 Homo sapiens 46-50 19215806-10 2009 In line with data from adult whole blood cultures, SFA proved to be a strong inhibitor of LPS-induced expression of IL-6 and TNF-alpha in the neonatal whole blood system. sanglifehrin A 51-54 interleukin 6 Homo sapiens 116-120