PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14996553-0	2004	Trichloroethanol enhances the activity of recombinant human TREK-1 and TRAAK channels.	2,2,2-trichloroethanol	0-16	potassium two pore domain channel subfamily K member 4	Homo sapiens	71-76	
14996553-3	2004	We have investigated the ability of 2,2,2-trichloroethanol (an active metabolite of the general anesthetic chloral hydrate (CH)) to modulate the activity of hTREK-1 and hTRAAK channels expressed heterologously in Chinese hamster ovary cells by using whole-cell patch-clamp recording.	2,2,2-trichloroethanol	36-58	potassium two pore domain channel subfamily K member 4	Homo sapiens	169-175	
14996553-4	2004	Trichloroethanol potentiated hTREK-1 and hTRAAK channel activity in a reversible, concentration-dependent manner.	2,2,2-trichloroethanol	0-16	potassium two pore domain channel subfamily K member 4	Homo sapiens	41-47	
14996553-10	2004	Our findings identify TREK-1 and TRAAK channels as molecular targets for trichloroethanol and suggest that activation of these channels might contribute to the CNS depressant effects of CH.	2,2,2-trichloroethanol	73-89	potassium two pore domain channel subfamily K member 4	Homo sapiens	33-38