PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20466046-0	2010	7-Ketocholesterol and cholesterol-5alpha,6alpha-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways.	7-ketocholesterol	0-17	AKT serine/threonine kinase 1	Homo sapiens	181-184	
28710022-2	2017	7-ketocholesterol induced phosphorylation of Akt, and increase in the levels of cytosolic and nuclear NF-kappaB p65, cytosolic NF-kappaB p50 and cytosolic phosphorylated-IkappaB-alpha in PC12 cells.	7-ketocholesterol	0-17	AKT serine/threonine kinase 1	Homo sapiens	45-48	
27740938-0	2016	7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells.	7-ketocholesterol	0-17	AKT serine/threonine kinase 1	Homo sapiens	51-54	
18495460-0	2009	Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis.	7-ketocholesterol	128-145	AKT serine/threonine kinase 1	Homo sapiens	56-59	
19157829-7	2010	Concomitantly, it inhibited 7-KC-induced apoptosis, by limiting caspase-3 activation and the modulatory effects of 7-KC on AKT, Bcl-2, Bcl-xL and Bax.	7-ketocholesterol	115-119	AKT serine/threonine kinase 1	Homo sapiens	123-126	
17172800-4	2007	Tumor necrosis factor-alpha (TNF-alpha), insulin-like growth factor-1 (IGF-1), and 7-ketocholesterol can regulate the expression of autophagic genes, including microtubule-associated protein 1 light chain-3 (MAP1LC3) and Beclin 1, through Akt/PKB and c-jun N-terminal signal pathways in VSMCs.	7-ketocholesterol	83-100	AKT serine/threonine kinase 1	Homo sapiens	239-246