PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24463558-4 2014 By Western blotting and flow cytometry, atherogenic stimulation of Smpd1+/+ CASMCs with 7-ketocholesterol was found to significantly enhance LC3B expression and increase the content of both APs and autophagolysosomes (APLs). 7-ketocholesterol 88-105 microtubule-associated protein 1 light chain 3 beta Mus musculus 141-145 24463558-5 2014 In Smpd1-/- CASMCs, such 7-ketocholesterol-induced increases in LC3B and p62 expression and APs were further augmented, but APLs formation was abolished. 7-ketocholesterol 25-42 microtubule-associated protein 1 light chain 3 beta Mus musculus 64-68 24463558-6 2014 Analysis of fluorescence resonance energy transfer between fluorescence-labeled LC3B and Lamp1 (lysosome marker) showed that 7-ketocholesterol markedly induced fusion of APs with lysosomes in Smpd1+/+ CASMCs, which was abolished in Smpd1-/- CASMCs. 7-ketocholesterol 125-142 microtubule-associated protein 1 light chain 3 beta Mus musculus 80-84 24095928-4 2013 Pharmacological or genetic inhibition of dynein activity dramatically enhanced 7-ketocholesterol (7-Ket)-induced expression of the autophagic marker LC3B and increased the cellular levels of p62, a selective substrate for autophagy. 7-ketocholesterol 79-96 microtubule-associated protein 1 light chain 3 beta Mus musculus 149-153 24445604-5 2014 In primary cultured CAMs, CD38 gene deletion markedly enhanced 7-ketocholesterol (7-Ket, an atherogenic stimulus and autophagy inducer)-induced accumulation of autophagosomes and increased expression of an autophagic marker, LC3B. 7-ketocholesterol 63-80 microtubule-associated protein 1 light chain 3 beta Mus musculus 225-229 24095928-4 2013 Pharmacological or genetic inhibition of dynein activity dramatically enhanced 7-ketocholesterol (7-Ket)-induced expression of the autophagic marker LC3B and increased the cellular levels of p62, a selective substrate for autophagy. 7-ketocholesterol 98-103 microtubule-associated protein 1 light chain 3 beta Mus musculus 149-153