PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12393025-7 2002 The results showed a significantly higher degree of decrease in platelet counts and elevated serum TPO in patients receiving CIFN 9 or 3 &mgr;g as compared with placebo at week 12 and week 24 of treatment, respectively. Adenosine Monophosphate 138-141 thrombopoietin Homo sapiens 99-102 11514400-4 2001 METHODS: We measured TPO (R&D Systems) in serum of 160 thrombocytopenic patients referred to our department for platelet life span isotopic studies. Adenosine Monophosphate 28-31 thrombopoietin Homo sapiens 21-24 30422039-3 2019 While these trials do suggest that TPO-mimetics are efficacious at increasing platelet counts in patients with CLD and have led to several recent drug approvals in this space by the U.S. Food & Drug Administration, it remains unclear whether these results translate to the relevant clinical endpoint of reduced perioperative bleeding rate and severity. Adenosine Monophosphate 193-196 thrombopoietin Homo sapiens 35-38