PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30909697-3 2019 Recently, advances in biologic therapy enabled blocking of IL-1α, IL-1β, IL-18, and IL-33 with new monoclonal antibodies, soluble receptors, or recombinant binding proteins. Adenosine Monophosphate 64-67 interleukin 1 alpha Homo sapiens 59-63 2971671-4 1988 Addition of exogenous (PGE1 and PGE2, also analogues of AMP, or forskolin increased the specific binding of 125I-IL 1 alpha to fibroblasts. Adenosine Monophosphate 56-59 interleukin 1 alpha Homo sapiens 113-123 30909697-1 2019 IL-1 family represent a group of structurally related cytokines with prevailing pro-inflammatory (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β a IL-37γ) or anti-inflammatory (IL-1Ra, IL-36Ra, IL-38, IL-37) effects. Adenosine Monophosphate 103-106 interleukin 1 alpha Homo sapiens 0-4 30909697-1 2019 IL-1 family represent a group of structurally related cytokines with prevailing pro-inflammatory (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β a IL-37γ) or anti-inflammatory (IL-1Ra, IL-36Ra, IL-38, IL-37) effects. Adenosine Monophosphate 119-122 interleukin 1 alpha Homo sapiens 0-4 30909697-1 2019 IL-1 family represent a group of structurally related cytokines with prevailing pro-inflammatory (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β a IL-37γ) or anti-inflammatory (IL-1Ra, IL-36Ra, IL-38, IL-37) effects. Adenosine Monophosphate 119-122 interleukin 1 alpha Homo sapiens 0-4 30909697-1 2019 IL-1 family represent a group of structurally related cytokines with prevailing pro-inflammatory (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β a IL-37γ) or anti-inflammatory (IL-1Ra, IL-36Ra, IL-38, IL-37) effects. Adenosine Monophosphate 119-122 interleukin 1 alpha Homo sapiens 0-4 30909697-1 2019 IL-1 family represent a group of structurally related cytokines with prevailing pro-inflammatory (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β a IL-37γ) or anti-inflammatory (IL-1Ra, IL-36Ra, IL-38, IL-37) effects. Adenosine Monophosphate 119-122 interleukin 1 alpha Homo sapiens 0-4 29941796-7 2018 Of particular interest are three hallmark cytokines, IL-6, TNFα and IL-1β, which have been studied extensively in basic research, cell-receptor signaling and drug development. Adenosine Monophosphate 83-86 interleukin 1 alpha Homo sapiens 78-82 29941796-8 2018 The field of inflammasome-mediated neuroinflammation is an emerging area of MDD research that is providing new cellular insight into how macrophages mechanistically support cytokine-associated neuropathology, particularly in the case of IL-1β-associated inflammation in MDD. Adenosine Monophosphate 242-245 interleukin 1 alpha Homo sapiens 237-241 34930349-1 2021 BACKGROUND: To investigate the role of adenosine monophosphate (AMP)-activated protein kinase (AMPK) on the production of interleukin (IL)-8, monocyte chemoattractant protein (MCP)-1, prostaglandin E2 and F2alpha induced by IL-1beta in endometrial stromal cells (ESCs) following treatment with 5-aminoimidazole-4- carboxamide ribonucleoside (AICAR). Adenosine Monophosphate 64-67 interleukin 1 alpha Homo sapiens 224-232 28323859-0 2017 Diacerein inhibits the pro-atherogenic & pro-inflammatory effects of IL-1 on human keratinocytes & endothelial cells. Adenosine Monophosphate 40-43 interleukin 1 alpha Homo sapiens 73-77 28323859-0 2017 Diacerein inhibits the pro-atherogenic & pro-inflammatory effects of IL-1 on human keratinocytes & endothelial cells. Adenosine Monophosphate 102-105 interleukin 1 alpha Homo sapiens 73-77 23592003-5 2013 The frequency of the C/C genotype of IL-1alpha was 55% in CP patients, while in the control group it was 20% (p<0.0001). Adenosine Monophosphate 112-115 interleukin 1 alpha Homo sapiens 37-46 23202919-6 2012 Although the relationship between high inflammatory cytokine levels and low ACh levels need to be further investigated in the future, our data suggest that IL-1β, and cytokines induced by it, such as IL-17 and ACh, may be involved in the pathogenesis of MS. Adenosine Monophosphate 161-164 interleukin 1 alpha Homo sapiens 156-160 19602113-2 2010 A broad-spectrum AMP, calprotectin (a complex of S100A8 and S100A9 proteins), is expressed by oral epithelial cells and is up-regulated by interleukin-1alpha (IL-1alpha). Adenosine Monophosphate 17-20 interleukin 1 alpha Homo sapiens 139-157 19602113-2 2010 A broad-spectrum AMP, calprotectin (a complex of S100A8 and S100A9 proteins), is expressed by oral epithelial cells and is up-regulated by interleukin-1alpha (IL-1alpha). Adenosine Monophosphate 17-20 interleukin 1 alpha Homo sapiens 159-168 10733939-2 2000 Interleukin-1 (IL-1) beta release from Mφ in response to LPS, appears to be mediated by the autocrine/paracrine release of ATP via P2X7 receptor activation. Adenosine Monophosphate 41-44 interleukin 1 alpha Homo sapiens 0-13 29751535-7 2018 Furthermore, IL-1β-stimulated SW982 cells secreted less inflammatory cytokines (TNF-α and IL-6), which is associated with the downregulation of p38-mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK), and NF-κB pathways. Adenosine Monophosphate 18-21 interleukin 1 alpha Homo sapiens 13-17 23965971-5 2013 Irradiated HEM cells had the greatest fold of TNFalpha secretion (UVB: 109-fold, UVA + B: 103-fold & UVB+A: 130-fold) when co-exposed to IL1alpha. Adenosine Monophosphate 100-103 interleukin 1 alpha Homo sapiens 141-149 24152854-0 2013 Thermal water of Vetriolo, Trentino, inhibits the negative effect of interleukin-1β on nitric oxide production and apoptosis in human osteoarthritic chondrocyte. Adenosine Monophosphate 83-86 interleukin 1 alpha Homo sapiens 69-82 21083841-5 2011 MATERIAL & METHODS: IL1-Rs expression was analyzed at the levels of the protein and mRNA using immunofluorescent and real-time polymerase chain reaction methods, respectively. Adenosine Monophosphate 10-13 interleukin 1 alpha Homo sapiens 24-27 17549071-4 2007 Bacteria may also regulate AMP expression by inducing keratinocyte expression of the autonomous proinflammatory cytokine, interleukin-1alpha (IL-1alpha). Adenosine Monophosphate 27-30 interleukin 1 alpha Homo sapiens 122-140 17549071-4 2007 Bacteria may also regulate AMP expression by inducing keratinocyte expression of the autonomous proinflammatory cytokine, interleukin-1alpha (IL-1alpha). Adenosine Monophosphate 27-30 interleukin 1 alpha Homo sapiens 142-151 16885604-1 2006 BACKGROUND & OBJECTIVES: Interleukin-1 receptor antagonist (IL-1Ra) is a naturally occurring anti-inflammatory molecule that blocks action of IL-1. Adenosine Monophosphate 12-15 interleukin 1 alpha Homo sapiens 64-68 14687222-4 2004 We found that pre-treatment of hGF with 5"-AMP induced marked inhibition of granulocyte-macrophage colony-stimulating factor (GM-CSF) production from hGF upon stimulation with interleukin-1alpha (IL-1alpha) by enzyme-linked immunosorbent assay (ELISA). Adenosine Monophosphate 40-46 interleukin 1 alpha Homo sapiens 176-194 14687222-4 2004 We found that pre-treatment of hGF with 5"-AMP induced marked inhibition of granulocyte-macrophage colony-stimulating factor (GM-CSF) production from hGF upon stimulation with interleukin-1alpha (IL-1alpha) by enzyme-linked immunosorbent assay (ELISA). Adenosine Monophosphate 40-46 interleukin 1 alpha Homo sapiens 196-205 11606496-1 2001 BACKGROUND & AIMS: Interleukin (IL)-1 gene cluster proinflammatory polymorphisms have been associated with development of gastric atrophy and with increased risk of gastric carcinoma. Adenosine Monophosphate 12-15 interleukin 1 alpha Homo sapiens 23-41 16873161-3 1996 There was a positive correlation between concentrations of IL-1β and IL-6. Adenosine Monophosphate 64-67 interleukin 1 alpha Homo sapiens 59-63 7989466-7 1994 ET production was also stimulated by transforming growth factor-beta 1 (2, 5 & 10 ng/mL) and IL-1 alpha (10 & 100 IU/mL) under serum-free conditions but always to a lesser extent than stimulation by serum. Adenosine Monophosphate 113-116 interleukin 1 alpha Homo sapiens 97-107