PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25262712-2 2014 OBJECTIVE: The aim of this study was to evaluate the prognostic influence of R1 and R0 resection on >5-year survival in patients with PDAC. Adenosine Monophosphate 101-104 ribonucleotide reductase catalytic subunit M1 Homo sapiens 77-86 31068300-9 2019 Transfection with the specific siRNAs significantly reduced the expression of RRM1 in MCF-7/R cells (P < 0.05), which showed a significantly lower IC50 value of paclitaxel than the cells transfected with the negative control siRNA (P < 0.05). Adenosine Monophosphate 104-107 ribonucleotide reductase catalytic subunit M1 Homo sapiens 78-82 31068300-10 2019 RRM1 silencing significantly inhibited the proliferation (P < 0.01) and enhanced the apoptosis-inducing effect of paclitaxel in MCF-7/R cells (P < 0.001); RRM1 silencing also resulted in obviously reduced Akt phosphorylation, suppressed Bcl-2 expression and promoted the expression of p53 protein in MCF-7/R cells. Adenosine Monophosphate 61-64 ribonucleotide reductase catalytic subunit M1 Homo sapiens 0-4 24024897-2 2013 MATERIALS & METHODS: In the current study, we sequenced the genes RRM1 and RRM2 in genomic DNA from HapMap cell lines with European (Utah residents with northern and western European ancestry [CEU]; n = 90) or African (Yoruba people in Ibadan, Nigeria [YRI]; n = 90) ancestry. Adenosine Monophosphate 11-14 ribonucleotide reductase catalytic subunit M1 Homo sapiens 70-74