PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32727432-14 2020 In the subgroup with normal weight, higher serum IGF-1 SDS (p = 0.009) and DHEAS SDS (p = 0.003) affected BA advancement independent of BMI SDS. Barium 106-108 insulin like growth factor 1 Homo sapiens 49-54 32855970-7 2020 A nonlinear relationship was observed between the IGF-1 standard deviation score (IGF-1 SDS) and BA-CA before and after GH therapy. Barium 97-99 insulin like growth factor 1 Homo sapiens 50-55 32855970-7 2020 A nonlinear relationship was observed between the IGF-1 standard deviation score (IGF-1 SDS) and BA-CA before and after GH therapy. Barium 97-99 insulin like growth factor 1 Homo sapiens 82-87 32855970-8 2020 Before GH therapy, there was a significant positive association between the IGF-1 SDS and BA-CA when the IGF-1 level was greater than -2 SDS (beta 0.17, 95% CI 0.08, 027; P < 0.001). Barium 90-92 insulin like growth factor 1 Homo sapiens 76-81 32855970-8 2020 Before GH therapy, there was a significant positive association between the IGF-1 SDS and BA-CA when the IGF-1 level was greater than -2 SDS (beta 0.17, 95% CI 0.08, 027; P < 0.001). Barium 90-92 insulin like growth factor 1 Homo sapiens 105-110 32855970-10 2020 After GH therapy, there was a significant positive association between the IGF-1 SDS and BA-CA when the IGF-1 level was lower than 2 SDS (beta 0.20, 95% CI 0.12, 028; P < 0.001). Barium 89-91 insulin like growth factor 1 Homo sapiens 75-80 32855970-10 2020 After GH therapy, there was a significant positive association between the IGF-1 SDS and BA-CA when the IGF-1 level was lower than 2 SDS (beta 0.20, 95% CI 0.12, 028; P < 0.001). Barium 89-91 insulin like growth factor 1 Homo sapiens 104-109 32855970-13 2020 There is a nonlinear relationship between IGF-1 and BA maturation in short children before and after GH treatment. Barium 52-54 insulin like growth factor 1 Homo sapiens 42-47 32855970-14 2020 These findings suggest that a low level of IGF-1 may contribute to BA delay in short children and adolescents. Barium 67-69 insulin like growth factor 1 Homo sapiens 43-48 32727432-9 2020 The advanced BA group had significantly higher BMI SDS, serum DHEAS SDS, IGF-1 SDS, androstenedione and fasting insulin and significantly lower sex hormone binding globulin (all p < 0.001). Barium 13-15 insulin like growth factor 1 Homo sapiens 73-78 32727432-11 2020 In the multiple linear regression model, serum IGF-1 SDS, BMI SDS and DHEAS SDS were the strongest predictors of advanced BA, accounting for 19.3% of the variance. Barium 122-124 insulin like growth factor 1 Homo sapiens 47-52 34256051-8 2021 There were differences in IGF-1 values between the CA and BA groups at the age of 10-11 years for boys and 7-11 years for girls. Barium 58-60 insulin like growth factor 1 Homo sapiens 26-31 34256051-11 2021 CONCLUSIONS: There is a significant difference between BA and CA in evaluating IGF-1 levels in children, which can significantly reduce the proportion of IGF-1 values above the upper limit of the kit reference range in children. Barium 55-57 insulin like growth factor 1 Homo sapiens 79-84 34256051-11 2021 CONCLUSIONS: There is a significant difference between BA and CA in evaluating IGF-1 levels in children, which can significantly reduce the proportion of IGF-1 values above the upper limit of the kit reference range in children. Barium 55-57 insulin like growth factor 1 Homo sapiens 154-159 34256051-12 2021 This suggests that children with BA advanced in pubertal period, the evaluating results of IGF-1 should be corrected by using BA. Barium 33-35 insulin like growth factor 1 Homo sapiens 91-96 34256051-12 2021 This suggests that children with BA advanced in pubertal period, the evaluating results of IGF-1 should be corrected by using BA. Barium 126-128 insulin like growth factor 1 Homo sapiens 91-96 32727432-17 2020 Age-specific serum IGF-1 SDS and DHEAS SDS were risk factors for BA advancement independent of BMI. Barium 65-67 insulin like growth factor 1 Homo sapiens 19-24