PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16286459-4 2006 Cleavage of VWF by recombinant ADAMTS13 was activated up to approximately 200-fold by zinc ions (K(D) (app) approximately 0.5 microM), calcium ions (K(D) (app) approximately 4.8 microM), and barium ions (K(D) (app) approximately 1.7 mM). Barium 191-197 ADAM metallopeptidase with thrombospondin type 1 motif 13 Homo sapiens 31-39 16286459-5 2006 Barium ions stimulated ADAMTS13 activity in citrated plasma but not in citrate-free plasma. Barium 0-6 ADAM metallopeptidase with thrombospondin type 1 motif 13 Homo sapiens 23-31 16286459-6 2006 Therefore, the stimulation by barium ions of ADAMTS13 in citrated plasma appears to reflect the release of chelated calcium and zinc ions from complexes with citrate. Barium 30-36 ADAM metallopeptidase with thrombospondin type 1 motif 13 Homo sapiens 45-53