PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25541203-0 2015 Selective binding to monoamine oxidase A: in vitro and in vivo evaluation of (18)F-labeled beta-carboline derivatives. norharman 91-105 monoamine oxidase A Homo sapiens 21-40 25770611-6 2015 The MAO-A is inhibited by all three tested beta-carbolines (harmane, norharmane, and harmaline) while MAO-B is inhibited only by norharmane. norharman 69-79 monoamine oxidase A Homo sapiens 4-9 25770611-7 2015 The presence of norharmane in mixtures of beta-carbolines can be identified based on the difference between the cumulative inhibition of MAO-A by all beta-carbolines and MAO-B inhibition. norharman 16-26 monoamine oxidase A Homo sapiens 137-142 8990278-0 1997 Inhibition of monoamine oxidase A by beta-carboline derivatives. norharman 37-51 monoamine oxidase A Homo sapiens 14-33 21992679-5 2012 Clorgyline and the beta-carbolines, harman and norharman, inhibited the oxidation of MPTP by MAO-A. norharman 47-56 monoamine oxidase A Homo sapiens 93-98 21992679-6 2012 Cigarette smoke, as well as the naturally occurring beta-carbolines (norharman and harman) isolated from smoke and coffee inhibited the oxidation of MPTP by MAO-B and/or MAO-A, suggesting protective effects against MPTP. norharman 69-78 monoamine oxidase A Homo sapiens 170-175 16139309-5 2006 Subsequently, the pyrido-indole (beta-carboline) alkaloids, norharman and harman, were identified and isolated from MAO-inhibiting coffee, and were good inhibitors on MAO A (harman and norharman) and MAO B (norharman) isozymes. norharman 60-69 monoamine oxidase A Homo sapiens 167-172 16139309-5 2006 Subsequently, the pyrido-indole (beta-carboline) alkaloids, norharman and harman, were identified and isolated from MAO-inhibiting coffee, and were good inhibitors on MAO A (harman and norharman) and MAO B (norharman) isozymes. norharman 185-194 monoamine oxidase A Homo sapiens 167-172 16139309-5 2006 Subsequently, the pyrido-indole (beta-carboline) alkaloids, norharman and harman, were identified and isolated from MAO-inhibiting coffee, and were good inhibitors on MAO A (harman and norharman) and MAO B (norharman) isozymes. norharman 185-194 monoamine oxidase A Homo sapiens 167-172 15582589-8 2005 Norharman was an inhibitor of MAO-A (K(i)=1.2+/-0.18 microM) and MAO-B (K(i)=1.12+/-0.19 microM), and harman of MAO-A (K(i)=55.54+/-5.3nM). norharman 0-9 monoamine oxidase A Homo sapiens 30-35 15582589-8 2005 Norharman was an inhibitor of MAO-A (K(i)=1.2+/-0.18 microM) and MAO-B (K(i)=1.12+/-0.19 microM), and harman of MAO-A (K(i)=55.54+/-5.3nM). norharman 0-9 monoamine oxidase A Homo sapiens 112-117 8990278-2 1997 The interaction of nine beta-carboline derivatives and four 3,4-dihydro forms with purified MAO A was investigated. norharman 24-38 monoamine oxidase A Homo sapiens 92-97 33339338-1 2020 The beta-carboline alkaloid harmine is a potent DYRK1A inhibitor, but suffers from undesired potent inhibition of MAO-A, which strongly limits its application. norharman 4-18 monoamine oxidase A Homo sapiens 114-119