PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12668004-1 2003 The SAR of a series of beta-carboline derived type 5 phosphodiesterase inhibitors has been explored and we have discovered compounds with excellent levels of PDE5 potency and selectivity over PDE6. norharman 23-37 phosphodiesterase 5A Homo sapiens 158-162 23117589-0 2012 Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel beta-carboline derivatives. norharman 98-112 phosphodiesterase 5A Homo sapiens 14-18