PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29387014-0 2018 Inhibiting beta-Catenin by beta-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy. norharman 27-41 catenin beta 1 Homo sapiens 11-23 29387014-5 2018 In the present study, we utilized SP141 as an exemplary beta-carboline compound to characterize beta-catenin as a molecular target of the beta-carboline compounds and to demonstrate an important role of beta-catenin in the anticancer activity of beta-carboline. norharman 138-152 catenin beta 1 Homo sapiens 96-108 29387014-5 2018 In the present study, we utilized SP141 as an exemplary beta-carboline compound to characterize beta-catenin as a molecular target of the beta-carboline compounds and to demonstrate an important role of beta-catenin in the anticancer activity of beta-carboline. norharman 138-152 catenin beta 1 Homo sapiens 96-108 29387014-10 2018 We envision that beta-carboline derivatives can be developed as promising dual inhibitors of beta-catenin and MDM2 for the treatment of advanced pancreatic cancer. norharman 17-31 catenin beta 1 Homo sapiens 93-105