PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10811733-3 2000 The P2X purinoceptor blocker, suramin (50 microM) or a nicotinic ACh receptor (nAChR) blocker (hexamethonium, 100 microM; mecamylamine, 1 microM) only partially inhibited these responses, but together, blocked almost all activity. Hexamethonium 95-108 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 79-84 9359598-5 1997 - 60 mV), ACh induced a hexamethonium-sensitive, inward current (IACh), mimicked by nicotine application, suggesting the presence of neuronal nicotinic acetylcholine receptors (nAChR). Hexamethonium 24-37 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 142-175 9359598-5 1997 - 60 mV), ACh induced a hexamethonium-sensitive, inward current (IACh), mimicked by nicotine application, suggesting the presence of neuronal nicotinic acetylcholine receptors (nAChR). Hexamethonium 24-37 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 177-182 22127290-6 2012 This response was diminished reversibly by the non-selective nAChR blocker hexamethonium, by the selective alpha7 blocker alpha-bungarotoxin and by the alpha4-containing nAChR blocker erysodine. Hexamethonium 75-88 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 61-66 18567834-6 2008 The subunit-nonselective nAChR antagonist hexamethonium (100 micromol/kg) and the selective alpha7-subunit antagonist methyllycaconitine (MLA; 3 and 10 micromol/kg) decreased the nicotine-induced tachycardia by 100 and 40%, respectively (maximal effects), suggesting that nAChRs containing the alpha7-subunit account for 40% of the nicotine-induced tachycardia. Hexamethonium 42-55 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 25-30 17727820-4 2007 The classical antagonists, hexamethonium and decamethonium, differentiate between peripheral nAChR subtypes. Hexamethonium 27-40 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 93-98 12740863-4 2003 The rank potency order of nAChR antagonists to reduce tetanic peak tension was alpha-bungarotoxin > d-tubocurarine >> mecamylamine > hexamethonium. Hexamethonium 145-158 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 26-31 34924113-4 2022 A 100 muM of nicotine-induced increase in neurite numbers depended on the exposure time and was inhibited by treatment with the nAChR antagonist hexamethonium (Hex) and alpha7 nAChR antagonist alpha-bungarotoxin (alpha-Bgtx). Hexamethonium 145-158 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 128-133 34924113-4 2022 A 100 muM of nicotine-induced increase in neurite numbers depended on the exposure time and was inhibited by treatment with the nAChR antagonist hexamethonium (Hex) and alpha7 nAChR antagonist alpha-bungarotoxin (alpha-Bgtx). Hexamethonium 160-163 cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus 128-133