PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1981792-3	1990	When arginine vasopressin was infused intravenously at a rate of 12.5 ng/(kg.min), the increase in hindquarter resistance, calculated as arterial pressure divided by hindquarter flow, was significantly (p less than 0.005) augmented after ganglionic blockade with hexamethonium in SHR but not in NCR.	Hexamethonium	263-276	arginine vasopressin	Rattus norvegicus	14-25	
8447490-4	1993	During autonomic blockade with methscopolamine and hexamethonium, the pressor sensitivities to AVP and [Phe2,Orn8]oxytocin were similarly increased.	Hexamethonium	51-64	arginine vasopressin	Rattus norvegicus	95-98	
1681990-5	1991	Acetylcholine at concentrations of 1 to 100 nM caused a dose-dependent, rapid increase in AVP, whereas AVP release induced by 10 nM acetylcholine was completely suppressed by the combined presence of 10 microM hexamethonium, a nicotinic receptor antagonist, and 50 microM atropine, a muscarinic receptor antagonist.	Hexamethonium	210-223	arginine vasopressin	Rattus norvegicus	90-93	
1681990-5	1991	Acetylcholine at concentrations of 1 to 100 nM caused a dose-dependent, rapid increase in AVP, whereas AVP release induced by 10 nM acetylcholine was completely suppressed by the combined presence of 10 microM hexamethonium, a nicotinic receptor antagonist, and 50 microM atropine, a muscarinic receptor antagonist.	Hexamethonium	210-223	arginine vasopressin	Rattus norvegicus	103-106	
2912212-4	1989	In contrast, in anesthesized rats the arterial pressor response to intrathecal AVP was blocked by intrathecal V1-ANT, intravenous hexamethonium, and intravenous phenoxybenzamine.	Hexamethonium	130-143	arginine vasopressin	Rattus norvegicus	79-82	
3346065-5	1988	The pressor response to vasopressin, but not to Ang II or norepinephrine, was greater in dexamethasone-treated than in vehicle-treated animals, and this difference became more pronounced in rats that received hexamethonium and MK 421.	Hexamethonium	209-222	arginine vasopressin	Rattus norvegicus	24-35	
2566102-5	1989	In contrast, the hemodynamic response to hypertonic saline was totally reverted when the vasopressin antagonist was injected in the hexamethonium-pretreated rats.	Hexamethonium	132-145	arginine vasopressin	Rattus norvegicus	89-100	
2892605-7	1988	Interruption of the sympathetic nervous system and the vascular action of vasopressin with intravenous hexamethonium and d(CH2)5Tyr(Me)arginine vasopressin attenuated the pressor and natriuretic responses to intracerebroventricular high Na+ CSF.	Hexamethonium	103-116	arginine vasopressin	Rattus norvegicus	74-85	
3826404-5	1987	Ganglionic blockade with methscopolamine and hexamethonium resulted in nearly a 60-fold enhancement of vasopressin pressor sensitivity.	Hexamethonium	45-58	arginine vasopressin	Rattus norvegicus	103-114	
3794328-5	1986	Ganglionic blockade with hexamethonium and atropine produced equivalent decreases in arterial pressure and increases in plasma vasopressin concentration in the two groups of rats.	Hexamethonium	25-38	arginine vasopressin	Rattus norvegicus	127-138	
2874742-3	1986	Hexamethonium did, however, block the increase in blood pressure, the decrease in heart rate, and the very small elevation in the plasma vasopressin concentration induced by nicotine (10 micrograms icv).	Hexamethonium	0-13	arginine vasopressin	Rattus norvegicus	137-148	
2880306-5	1986	Hexamethonium, but not atropine, prevented the increase in VP release produced by increased osmolality of the hypothalamus side culture medium.	Hexamethonium	0-13	arginine vasopressin	Rattus norvegicus	59-61	
6123262-6	1982	Plasma norepinephrine and epinephrine levels were not altered by PGF2 alpha-icv in hexamethonium-treated rats, but plasma vasopressin concentration was markedly elevated in all hexamethonium-infused rats.	Hexamethonium	177-190	arginine vasopressin	Rattus norvegicus	122-133	
6115624-3	1981	Alpha adrenoceptor antagonists, hexamethonium and 6-hydroxydopamine diminished the effectiveness of low acetylcholine concentrations on normal and castrated preparations of the epididymal portion of isolated rat vas deferens, but did not influence the maximal response.	Hexamethonium	32-45	arginine vasopressin	Rattus norvegicus	212-215	
456315-2	1979	Nicotinic blocking agents, hexamethonium, tetraethylammonium chloride, and trimethaphan, blocked VP release in response to the addition of sufficient NaCl to yield a 10 mosm/kg H2O increase in culture medium osmolality.	Hexamethonium	27-40	arginine vasopressin	Rattus norvegicus	97-99	
436724-2	1979	Nicotinic antagonists, hexamethonium, tetraethylammonium chloride, and trimethaphan blocked VP release in response to acetylcholine and nicotine.	Hexamethonium	23-36	arginine vasopressin	Rattus norvegicus	92-94	
26843857-10	2016	Moreover, the inhibitory effect of AVP (180 pmol) on gastric motility could be blocked completely by both SR49059 (320 pmol) and hexamethonium (8 mumol).	Hexamethonium	129-142	arginine vasopressin	Rattus norvegicus	35-38