PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25617597-6	2015	Labeling of lt14a with an Alexa Fluor 488 ester showed that lt14a was bound to the surface of PC12 cells and that this binding was inhibited by pre-application of the nicotinic acetylcholine receptor (nAChR) antagonist tubocurarine chloride (TUB) and the nAChR blocker hexamethonium bromide (HB).	Hexamethonium	269-290	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	167-199	
1715014-4	1991	The apparent mean open time of the AChR channel, as estimated from the power density spectrum of the ACh-induced current fluctuations at -90 mV, was not decreased by 2 microM (+)-sparteine, in contrast to what was observed with hexamethonium, the well known open-channel blocker for ganglionic AChRs.	Hexamethonium	228-241	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	35-39	
33456504-8	2021	The muscarinic acetylcholine receptor (mAChR) antagonist atropine (ATR; 100 nM) and the nicotinic acetylcholine receptor (nAChR) antagonist hexamethonium (HEM; 50 microM) were administered 10 min before APC.	Hexamethonium	140-153	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	122-127	
25617597-6	2015	Labeling of lt14a with an Alexa Fluor 488 ester showed that lt14a was bound to the surface of PC12 cells and that this binding was inhibited by pre-application of the nicotinic acetylcholine receptor (nAChR) antagonist tubocurarine chloride (TUB) and the nAChR blocker hexamethonium bromide (HB).	Hexamethonium	269-290	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	201-206	
25617597-6	2015	Labeling of lt14a with an Alexa Fluor 488 ester showed that lt14a was bound to the surface of PC12 cells and that this binding was inhibited by pre-application of the nicotinic acetylcholine receptor (nAChR) antagonist tubocurarine chloride (TUB) and the nAChR blocker hexamethonium bromide (HB).	Hexamethonium	292-294	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	167-199	
25617597-6	2015	Labeling of lt14a with an Alexa Fluor 488 ester showed that lt14a was bound to the surface of PC12 cells and that this binding was inhibited by pre-application of the nicotinic acetylcholine receptor (nAChR) antagonist tubocurarine chloride (TUB) and the nAChR blocker hexamethonium bromide (HB).	Hexamethonium	292-294	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	201-206	
22085992-10	2012	The nicotinic-acetylcholine receptor (nAChR) blocker hexamethonium induced a significant inhibition of the [(3)H]dopamine release produced by CC in PC12 cells but the TZ-elicited release of [(3)H]dopamine was 70% hexamethonium-insensitive, suggesting unidentified TZ toxins affecting other regulatory mechanisms of catecholamine secretion.	Hexamethonium	53-66	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	4-36	
25514605-7	2015	A pretreatment with nicotinic acetylcholine receptor antagonists hexamethonium, mecamylamine, and methyllycaconitine, but not dextrometorphan, canceled the TH-LI nerve reinnervation induced by nicotine.	Hexamethonium	65-78	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	20-52	
22085992-10	2012	The nicotinic-acetylcholine receptor (nAChR) blocker hexamethonium induced a significant inhibition of the [(3)H]dopamine release produced by CC in PC12 cells but the TZ-elicited release of [(3)H]dopamine was 70% hexamethonium-insensitive, suggesting unidentified TZ toxins affecting other regulatory mechanisms of catecholamine secretion.	Hexamethonium	53-66	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	38-43	
22085992-10	2012	The nicotinic-acetylcholine receptor (nAChR) blocker hexamethonium induced a significant inhibition of the [(3)H]dopamine release produced by CC in PC12 cells but the TZ-elicited release of [(3)H]dopamine was 70% hexamethonium-insensitive, suggesting unidentified TZ toxins affecting other regulatory mechanisms of catecholamine secretion.	Hexamethonium	213-226	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	4-36	
22085992-10	2012	The nicotinic-acetylcholine receptor (nAChR) blocker hexamethonium induced a significant inhibition of the [(3)H]dopamine release produced by CC in PC12 cells but the TZ-elicited release of [(3)H]dopamine was 70% hexamethonium-insensitive, suggesting unidentified TZ toxins affecting other regulatory mechanisms of catecholamine secretion.	Hexamethonium	213-226	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	38-43	
18423439-4	2008	In addition, the corticotropin-releasing factor-induced elevation of noradrenaline release in the hypothalamic paraventricular nucleus and plasma corticosterone were abolished by hexamethonium, a non-selective nicotinic acetylcholine receptor antagonist, at 1.8 micromol/animal, intracerebroventricularly, and alpha-conotoxin MII, a potent alpha(3)beta(2) nicotinic acetylcholine receptor antagonist, at 30 nmol/animal, i.c.v.	Hexamethonium	179-192	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	210-242	
18423439-4	2008	In addition, the corticotropin-releasing factor-induced elevation of noradrenaline release in the hypothalamic paraventricular nucleus and plasma corticosterone were abolished by hexamethonium, a non-selective nicotinic acetylcholine receptor antagonist, at 1.8 micromol/animal, intracerebroventricularly, and alpha-conotoxin MII, a potent alpha(3)beta(2) nicotinic acetylcholine receptor antagonist, at 30 nmol/animal, i.c.v.	Hexamethonium	179-192	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	356-388	
17286987-5	2007	Hexamethonium, an antagonist of nicotinic acetylcholine receptor (nAChR), inhibited nicotine-induced VEGF release.	Hexamethonium	0-13	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	32-64	
17286987-5	2007	Hexamethonium, an antagonist of nicotinic acetylcholine receptor (nAChR), inhibited nicotine-induced VEGF release.	Hexamethonium	0-13	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	66-71	
11731102-3	2001	In contrast, EPSPs were abolished by the nicotinic acetylcholine receptor antagonists, hexamethonium and mecamylamine.	Hexamethonium	87-100	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	41-73	
17141214-8	2007	The present results suggest that subchronic treatment with the nicotinic acetylcholine receptor antagonist hexamethonium reduces a GABA(A)-R mediated counteraction of the nucleus accumbens dopamine response to ethanol.	Hexamethonium	107-120	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	63-95	
9044380-7	1997	The nicotinic acetylcholine receptor antagonists (n-bungarotoxin > mecamylamine > (+)-tubocurarine > hexamethonium > alpha-bungarotoxin = dihydro-beta-erythroidine) and tetrodotoxin antagonized the effect of dimethylphenylpiperazinium to release [3H]noradrenaline.	Hexamethonium	110-123	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	4-36	
7574008-6	1995	Hexamethonium is known to be a weak antagonist at the postsynaptic nicotinic acetylcholine receptor but a potent antagonist at the presynaptic nicotinic receptor.	Hexamethonium	0-13	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	67-99