PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16603734-3 2006 We now report the genetic confirmation of this hypothesis through the construction of a conditional delta hgprt/delta xprt mutant strain that exhibits an absolute requirement for 2"-deoxycoformycin, an inhibitor of the leishmanial adenine aminohydrolase enzyme, and either adenine or adenosine as a source of purine. Pentostatin 179-197 xanthine phosphoribosyltransferase Leishmania donovani 118-122