PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19181531-1 2009 Calreticulin Transacetylase (CRTAase) catalyzes the transfer of acetyl groups from polyphenolic acetates (PAs) to the receptor proteins and modulates their biological activities. polyphenolic acetates 83-104 calreticulin Homo sapiens 0-12 22264757-1 2012 Calreticulin transacetylase (CRTAase) is known to catalyze the transfer of acetyl group from polyphenolic acetates (PA) to certain receptor proteins (RP), thus modulating their activity. polyphenolic acetates 93-114 calreticulin Homo sapiens 0-12 22130072-1 2012 Our earlier investigations culminated in the discovery of a unique membrane-bound enzyme Calreticulin transacetylase (CRTAase) in mammalian cells catalyzing the transfer of acetyl group from polyphenolic acetates (PAs) to certain functional proteins viz. polyphenolic acetates 191-212 calreticulin Homo sapiens 89-101 20600569-1 2010 Calreticulin Transacetylase (CRTAase) catalyzes the transfer of acetyl group(s) from polyphenolic acetates (PAs) to functional proteins, such as Glutathione S-transferase (GST), NADPH Cytochrome c reductase and Nitric Oxide Synthase (NOS) resulting in the modulation of biological activities. polyphenolic acetates 85-106 calreticulin Homo sapiens 0-12 20188080-0 2010 Calreticulin transacetylase catalyzed modification of the TNF-alpha mediated pathway in the human peripheral blood mononuclear cells by polyphenolic acetates. polyphenolic acetates 136-157 calreticulin Homo sapiens 0-12 20188080-4 2010 In previous investigations, we have conclusively established calreticulin transacetylase catalyzed activation of endothelial nitric oxide synthase (eNOS) by polyphenolic acetates. polyphenolic acetates 157-178 calreticulin Homo sapiens 61-73 20188080-5 2010 In the present work, calreticulin transacetylase of human peripheral blood mononuclear cells was characterized with respect to specificity for various polyphenolic acetates and its role in the activation of TNF-alpha induced nitric oxide synthase (iNOS). polyphenolic acetates 151-172 calreticulin Homo sapiens 21-33 28079009-5 2018 A recently identified novel transacetylase activity of CRT adds a new dimension to its multi-faceted involvement in cancer by virtue of polyphenolic acetates (PA): CRT transacetylase (CRTase) system which results in hyperacetylation of target proteins, thereby mimicking the effects of Histone deacetylase inhibitors (HDACi). polyphenolic acetates 136-157 calreticulin Homo sapiens 55-58 28079009-5 2018 A recently identified novel transacetylase activity of CRT adds a new dimension to its multi-faceted involvement in cancer by virtue of polyphenolic acetates (PA): CRT transacetylase (CRTase) system which results in hyperacetylation of target proteins, thereby mimicking the effects of Histone deacetylase inhibitors (HDACi). polyphenolic acetates 136-157 calreticulin Homo sapiens 164-167 24552186-1 2014 BACKGROUND AND AIMS: Polyphenolic acetates (PAs) have antioxidant/ pro-oxidant properties and can also acetylate proteins (enzymes) by a novel acetoxy drug: calreticulin transacetylase acetylation system. polyphenolic acetates 21-42 calreticulin Homo sapiens 157-169 25478886-8 2014 Emergence of calreticulin (CRT) mediated protein acetylation system using polyphenolic acetates as donors coupled with over expression of CRT has opened new avenues for targeting protein acetylation for improving cancer therapy. polyphenolic acetates 74-95 calreticulin Homo sapiens 13-25 25478886-8 2014 Emergence of calreticulin (CRT) mediated protein acetylation system using polyphenolic acetates as donors coupled with over expression of CRT has opened new avenues for targeting protein acetylation for improving cancer therapy. polyphenolic acetates 74-95 calreticulin Homo sapiens 27-30 34472223-2 2021 CRT shows higher transacetylase activity, as shown by us earlier, in the presence of the polyphenolic acetates (like 7, 8-diacetoxy-4-methylcoumarin, DAMC) and modifies the activity of a number of proteins, thereby influencing cell signaling. polyphenolic acetates 89-110 calreticulin Homo sapiens 0-3