PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15532723-1	2004	We previously reported that an actin-binding protein, cofilin, is involved in superoxide production, phagocytosis, and chemotaxis in activated phagocytes through cytoskeletal reorganization.	Superoxides	78-88	cofilin 1	Homo sapiens	54-61	
17130184-3	2007	We reported recently that cofilin plays a regulatory role in superoxide production and phagocytosis by leukocytes, and in the present study, we investigated the role of cofilin in the chemotaxis of neutrophilic HL-60 cells.	Superoxides	61-71	cofilin 1	Homo sapiens	26-33	
11257443-1	2001	Cofilin, an actin-binding protein, plays an important role in the migration, phagocytosis, and superoxide production of activated phagocytes through cytoskeletal reorganization.	Superoxides	95-105	cofilin 1	Homo sapiens	0-7	
7642640-10	1995	Furthermore, confocal laser scanning microscopy showed that cofilin existed diffusely in the cytosol and nuclear region of the resting cells, while in the activated cells, it was accumulated at the plasma membrane area, forming ruffles or endocytic vesicles on which O2.- should be produced.	Superoxides	267-269	cofilin 1	Homo sapiens	60-67	
34294886-7	2022	Moreover, we revealed that co-administration of CEP and epirubicin markedly increased the generation of mitochondrial superoxide, resulting in oxidation of the actin-remodeling protein cofilin, which promoted formation of an intramolecular disulfide bridge between Cys39 and Cys80 as well as Ser3 dephosphorylation, leading to mitochondria translocation of cofilin, thus causing mitochondrial fission and apoptosis.	Superoxides	118-128	cofilin 1	Homo sapiens	185-192	
34294886-7	2022	Moreover, we revealed that co-administration of CEP and epirubicin markedly increased the generation of mitochondrial superoxide, resulting in oxidation of the actin-remodeling protein cofilin, which promoted formation of an intramolecular disulfide bridge between Cys39 and Cys80 as well as Ser3 dephosphorylation, leading to mitochondria translocation of cofilin, thus causing mitochondrial fission and apoptosis.	Superoxides	118-128	cofilin 1	Homo sapiens	357-364	
10220580-1	1999	We studied the roles of cofilin, an actin-binding phosphoprotein, in superoxide production of neutrophil-like HL-60 cells triggered by opsonized zymosan (OZ).	Superoxides	69-79	cofilin 1	Homo sapiens	24-31	
10220580-11	1999	Furthermore, in a superoxide-producing cell-free system employing membranous and cytosolic fractions, affinity-purified anti-cofilin antibody showed an enhancing effect.	Superoxides	18-28	cofilin 1	Homo sapiens	125-132	
10220580-12	1999	These results suggest that cofilin participates in the superoxide production of the OZ-activated phagocytes through dephosphorylation and translocation.	Superoxides	55-65	cofilin 1	Homo sapiens	27-34