PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35247490-4 2022 More importantly, the nanocarrier could enhance the cascade reaction between SOD and CAT, which converts the superoxide anion to oxygen. Superoxides 109-125 catalase Mus musculus 85-88 9749602-7 1998 Because SOD1 dismutates superoxide to H2O2, overexpression of SOD1 in the presence of developmentally low activities of the catalytic enzymes glutathione peroxidase and catalase leads to an increased production of H2O2, and may explain the increased brain injury observed after hypoxia-ischemia in neonatal SOD1 mice. Superoxides 24-34 catalase Mus musculus 169-177 1707707-20 1990 Intraperitoneal administration of a mixture of superoxide dismutase and catalase reduced detectable superoxide anion by 98% without inhibiting the writhing response to zymosan or the antinociceptive potency of paracetamol. Superoxides 100-116 catalase Mus musculus 72-80 9778146-7 1998 Superoxide dismutase and catalase, which stabilise NO by removing superoxide anion, ameliorated the potentiation of the NMDA-mediated death of CGC in co-culture with immunostimulated microglia, implying that reactions of NO with superoxide to form peroxynitrite can be implicated in the potentiated neurotoxicity. Superoxides 66-82 catalase Mus musculus 25-33 9778146-7 1998 Superoxide dismutase and catalase, which stabilise NO by removing superoxide anion, ameliorated the potentiation of the NMDA-mediated death of CGC in co-culture with immunostimulated microglia, implying that reactions of NO with superoxide to form peroxynitrite can be implicated in the potentiated neurotoxicity. Superoxides 66-76 catalase Mus musculus 25-33 7504486-4 1993 The protective effects of catalase and superoxide dismutase indicate that superoxide radical and hydrogen peroxide being formed during autooxidation of the complex are involved in cell damage. Superoxides 74-92 catalase Mus musculus 26-34 31849213-6 2020 Catalase (CAT) was encapsulated to catalyze the production of oxygen (O2) from H2O2. Superoxides 70-72 catalase Mus musculus 0-8 31960567-4 2020 Co/PMCS can eliminate O2 - and H2O2 by mimicking superoxide dismutase, catalase and glutathione peroxidase, while remove OH via the oxidative-reduction cycle, exhibiting markedly higher activity than nanozymes. Superoxides 22-24 catalase Mus musculus 71-79 2990646-4 1985 The cell lysis by the superoxide-generating xanthine oxidase system was not significantly increased by SOD, but was significantly decreased by nitroblue tetrazolium and completely abolished by catalase. Superoxides 22-32 catalase Mus musculus 193-201 33197763-5 2021 Decreased activities of superoxide dismutase (SOD) and catalase (CAT) were markedly reversed upon treatment with cbFeD while levels of malondialdehyde (MDA) and glutathione (GSH) were significantly restored towards normal values. Superoxides 24-34 catalase Mus musculus 65-68 32841160-15 2020 Additionally, the activity of antioxidant enzymes superoxide dismutase, catalase, glutathione peroxidase and reduced glutathione was enhanced to 53.06, 40, 52.22 and 38.49%, respectively. Superoxides 50-60 catalase Mus musculus 72-80 31865110-3 2020 2019 Sep 5;220:117104) showed the effects of mercaptopropionic acid- CdTe quantum dots to the antioxidant enzymes catalase and superoxide dismutase molecules and then demonstrates the subsequent quantum dots toxic effects at a cellular level, and they proposed a mechanism of QD induced apoptosis and cell death involving oxidative stress, revealing their potential risk in the biomedical applications. Superoxides 127-137 catalase Mus musculus 114-122 31849213-6 2020 Catalase (CAT) was encapsulated to catalyze the production of oxygen (O2) from H2O2. Superoxides 70-72 catalase Mus musculus 10-13 28643395-1 2017 Catalase is an antioxidative enzyme that converts hydrogen peroxide (H2 O2 ) produced by superoxide dismutase from highly reactive superoxide (O2- ) to water and oxygen molecules. Superoxides 89-99 catalase Mus musculus 0-8 30849122-9 2019 Citrulline injected ip on day 4 PI with quinine-injected ip on day 6 PI partially protected mice from eCM; citrulline plus scavenging of superoxide with pegylated superoxide dismutase and pegylated catalase protected all recipients from eCM. Superoxides 137-147 catalase Mus musculus 198-206 29867936-9 2018 On the other hand, superoxide production in heart homogenates was elevated already in 6-month-old Tgalphaq*44 mice and progressively increased to high levels in 14-month-old Tgalphaq*44 mice, while the enzymatic activity of catalase, glutathione reductase, and glutathione peroxidase was all elevated as early as in 4-month-old Tgalphaq*44 mice and stayed at a similar level in 14-month-old Tgalphaq*44. Superoxides 19-29 catalase Mus musculus 224-232 31701714-9 2019 Compared with 21% O2 group, the expressions of Nrf2 mRNA and protein, antioxidant enzymes SOD1, SOD2, CAT, HO-1, NQO-1, GPX-1 mRNA were increased significantly (P<0.05 or P<0.01), and ROS level was lower (P<0.01) in 12%O2 group cells; only the expression of GPX-1 mRNA was increased (P<0.05) in 8%O2 group; the expressions of Nrf2 mRNA and protein expression, antioxidant enzymes SOD1, SOD2, NQO-1, GPX-1 mRNA were decreased significantly(P<0.05 or P<0.01), and ROS level was higher (P<0.01) in 5%O2 group. Superoxides 18-20 catalase Mus musculus 102-105 30608177-8 2019 Cigarette smoke and angiotensin II impaired endothelium-dependent relaxation and induced superoxide overproduction, which was diminished in mCAT mice. Superoxides 89-99 catalase Mus musculus 140-144 30319243-12 2018 Conclusion: Lactobacillus strains with dismutase-like activity are more effective in alleviating intestinal inflammation than strains producing catalase, suggesting that superoxide anion radical decomposition is crucial in this process. Superoxides 170-186 catalase Mus musculus 144-152 28645653-2 2017 Catalase, is an important endogenous antioxidant enzyme that catabolizes hydrogen peroxide produced by the dismutation of superoxide. Superoxides 122-132 catalase Mus musculus 0-8 24213612-6 2014 The data show that hydrogen peroxide (H2O2), but not superoxide anion (O2( -)), was increased in the early phases (within 6 h) of PAB in RV and that this increase was diminished by catalase and diphenyleneiodonium chloride but not by SOD, N(omega)-nitro-l-arginin methyl ester, febuxostat, or indomethacin. Superoxides 40-42 catalase Mus musculus 181-189 26069236-9 2015 SOD and catalase protected against superoxide-induced methionine oxidation and restored protein C activation in vitro (P<0.05). Superoxides 35-45 catalase Mus musculus 0-16 20876216-2 2011 Catalase and superoxide dismutase (SOD) conjugated with antibodies to platelet/endothelial cell adhesion molecule 1 (PECAM-1) bind specifically to endothelium and inhibit effects of corresponding ROS, H(2)O(2), and superoxide anion. Superoxides 215-231 catalase Mus musculus 0-8 19409565-8 2009 These observations, together with the functions of catalase and Cu/Zn-SOD to scavenge hydrogen peroxide and superoxide anions, implicate a causal role of ROS in the pathogenesis of BaP-induced atherosclerosis. Superoxides 108-125 catalase Mus musculus 51-59 14576080-3 2004 Adenovirus-mediated expression of superoxide dismutase and catalase inhibited TNF-alpha-induced MCP-1 gene expression, suggesting important roles of superoxide (O(2)(-).) Superoxides 161-165 catalase Mus musculus 59-67 23649652-1 2013 Manganese superoxide dismutase (MnSOD) catalyzes superoxide radical (O2 (-)) into hydrogen peroxide (H2O2), which is further catalyzed by the combined action of glutathione peroxidase (GPx) and catalase (CAT) into water and oxygen. Superoxides 49-67 catalase Mus musculus 194-202 23649652-1 2013 Manganese superoxide dismutase (MnSOD) catalyzes superoxide radical (O2 (-)) into hydrogen peroxide (H2O2), which is further catalyzed by the combined action of glutathione peroxidase (GPx) and catalase (CAT) into water and oxygen. Superoxides 49-67 catalase Mus musculus 204-207 21859962-4 2011 Stretch-induced fluorescence was reduced significantly (P<0.05) by incubation with Tempol (3.7+-0.8%), pegylated superoxide dismutase (3.2+-1.0%), or apocynin (3.5+-0.9%) but not by pegylated catalase, L-nitroarginine methylester, or Ca(2+)-free medium, relating it to Ca(2+)-independent vascular superoxide. Superoxides 116-126 catalase Mus musculus 195-203 19628743-8 2009 Administration of plasmids encoding SOD2 or CAT significantly reduced levels of superoxide ion, hydrogen peroxide, and 4-HNE. Superoxides 80-90 catalase Mus musculus 44-47 17194725-9 2007 The reduction in ANG II-mediated superoxide production in the medulla with CoPP was associated with a decrease in extracellular superoxide dismutase protein but an increase in catalase protein and activity. Superoxides 33-43 catalase Mus musculus 176-184 11117554-1 2000 Continuous subcutaneous administration of polyamine-modified catalase that has increased permeability at the blood-brain barrier showed both a highly significant delay in onset and an increase in survival in a transgenic mouse model of familial amyotrophic lateral sclerosis having a point mutation in the gene encoding copper/zinc superoxide dismutase. Superoxides 332-342 catalase Mus musculus 61-69 10443798-2 1999 The prevention of such biological damage can be achieved by dismutation of superoxide to H2O2 which in turn is removed by catalase and GSH peroxidase. Superoxides 75-85 catalase Mus musculus 122-130