PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22693641-7 2012 Furthermore, ACE2 deficiency led to greater increases in Ang II-mediated profilin-1 expression, NADPH oxidase activity, and superoxide and peroxynitrite production in the aortas of ACE2KO mice associated with enhanced phosphorylated levels of Akt, p70S6 kinase, extracellular signal-regulated kinases (ERK1/2) and endothelial nitric oxide synthase (eNOS). Superoxides 124-134 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Mus musculus 13-17 24728465-10 2014 Vascular superoxide and nitrotyrosine levels were increased in ACE2(+/-) vessels consistent with increased vascular oxidative stress. Superoxides 9-19 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Mus musculus 63-67 21285291-8 2011 Activation of Ang II-stimulated signalling pathways in the ACE2-deficient myocardium was associated with increased expression and phosphorylation of p47(phox), NADPH oxidase activity, and superoxide generation, leading to enhanced MMP-mediated degradation of the extracellular matrix. Superoxides 188-198 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Mus musculus 59-63