PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21418589-5 2011 The decrease in cellular O2-, which was accompanied by a brief accumulation of H2O2 and downregulation of phosphorylated Akt (p-Akt) and cellular FLICE-inhibitory protein, sensitized K562 leukemia cells and human promyelocytic leukemia (HL-60) cells to TRAIL-induced apoptosis. Superoxides 25-27 caspase 8 Homo sapiens 146-151 26337205-9 2015 Inhibiting glycolysis increased superoxide and blocked autophagy in apoptosis-resistant cells, causing p62-dependent caspase-8 activation. Superoxides 32-42 caspase 8 Homo sapiens 117-126 12370493-0 2002 Intracellular superoxide induces apoptosis in VSMCs: role of mitochondrial membrane potential, cytochrome C and caspases. Superoxides 14-24 caspase 8 Homo sapiens 112-120 25619142-6 2015 Singlet-oxygen-dependent activation of the FAS receptor and caspase-8 increased superoxide anion generation by NOX1 and amplification of singlet oxygen generation, which allowed singlet-oxygen-dependent inactivation of catalase. Superoxides 80-96 caspase 8 Homo sapiens 60-69