PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24523141-7	2014	This study demonstrates that combination of VEGF and PA can increase the permeability of the BTB by a paracellular pathway (downregulation of occludin and claudin-5) and a transcellular pathway (upregulation of caveolin-1 and caveolin-2) and that the cGMP/PKG/NF-kappaB signal pathway might be involved in the modulation process.	btb	93-96	caveolin 2	Rattus norvegicus	226-236	
21193965-6	2011	The time peak of expression level of caveolin-1 and caveolin-2 was identical with the peak time of permeability of the BTB and the density of pinocytotic vesicles.	btb	119-122	caveolin 2	Rattus norvegicus	52-62	
21193965-7	2011	All of these results strongly indicated that VEGF increased permeability of the BTB caused by enhancement of the density of pinocytotic vesicles, and the molecular mechanism might be associated with upregulated expression of caveolin-1 and caveolin-2.	btb	80-83	caveolin 2	Rattus norvegicus	240-250	
20146088-8	2010	This led to the conclusion that the BK-mediated BTB permeability increase resulting from augmentation of the quantity of pinocytotic vesicles (transcellular pathway) is associated with the significantly up-regulated expression of caveolin-1 and caveolin-2.	btb	48-51	caveolin 2	Rattus norvegicus	245-255	
24526454-13	2014	We suggest that low-dose EMAP-II can induce BTB hyperpermeability via the transcellular pathway, which is associated with phosphorylation and upregulation of caveolin-1 and caveolin-2 and involves the tyrosine kinase/RhoA/Rho kinase signaling pathway.	btb	44-47	caveolin 2	Rattus norvegicus	173-183