PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11248086-4 2001 By using combinations of knockout and transgenic animals, we show that activation of SXR/PXR is necessary and sufficient to both induce CYP3A enzymes and confer resistance to toxicity by LCA, as well as other xenotoxicants such as tribromoethanol and zoxazolamine. Zoxazolamine 251-263 nuclear receptor subfamily 1 group I member 2 Homo sapiens 85-88 11248086-4 2001 By using combinations of knockout and transgenic animals, we show that activation of SXR/PXR is necessary and sufficient to both induce CYP3A enzymes and confer resistance to toxicity by LCA, as well as other xenotoxicants such as tribromoethanol and zoxazolamine. Zoxazolamine 251-263 nuclear receptor subfamily 1 group I member 2 Homo sapiens 89-92