PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23868084-6 2013 Characterizing the zofenoprilat downstream effector we found that zofenoprilat reverted the SirT-1 downregulation induced by angiotensin II. zofenoprilate 19-31 sirtuin 1 Homo sapiens 92-98 23868084-6 2013 Characterizing the zofenoprilat downstream effector we found that zofenoprilat reverted the SirT-1 downregulation induced by angiotensin II. zofenoprilate 66-78 sirtuin 1 Homo sapiens 92-98 23868084-9 2013 SirT1 inhibition by sirtinol annulled zofenoprilat action while SirT1 overexpression reverted the cytotoxic effects of angiotensin II. zofenoprilate 38-50 sirtuin 1 Homo sapiens 0-5 23868084-10 2013 Finally, zofenoprilat negatively controlled angiotensin I receptor protein expression through SirT1. zofenoprilate 9-21 sirtuin 1 Homo sapiens 94-99