PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11934587-2 2002 The structure-based design of potent sulfonamide hydroxamate TACE inhibitors bearing novel acetylenic P1" groups has led to compounds with excellent in vitro potency against TACE and selectivity over MMP-1. acetylenic 91-101 matrix metallopeptidase 1 Homo sapiens 200-205