PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20932495-6 2011 Morphine and nicotine enhance CYP3A4 and MDR1 expression in vitro. Nicotine 13-21 ATP binding cassette subfamily B member 1 Homo sapiens 41-45 33329709-0 2020 Effects of Genetic Polymorphisms of Drug Transporter ABCB1 (MDR1) and Cytochrome P450 Enzymes CYP2A6, CYP2B6 on Nicotine Addiction and Smoking Cessation. Nicotine 112-120 ATP binding cassette subfamily B member 1 Homo sapiens 53-58 16191663-2 2005 Several recent studies have raised confounding results regarding the roles of P-gp in nicotine disposition. Nicotine 86-94 ATP binding cassette subfamily B member 1 Homo sapiens 78-82 16191663-3 2005 To ascertain this question, we examined the effects of nicotine and its major oxidative metabolite, cotinine, on ATPase activity using P-gp containing membranes, in which nicotine and cotinine-stimulated inorganic Pi was used as a marker of the binding affinity of nicotine and cotinine to P-gp. Nicotine 171-179 ATP binding cassette subfamily B member 1 Homo sapiens 135-139 16191663-3 2005 To ascertain this question, we examined the effects of nicotine and its major oxidative metabolite, cotinine, on ATPase activity using P-gp containing membranes, in which nicotine and cotinine-stimulated inorganic Pi was used as a marker of the binding affinity of nicotine and cotinine to P-gp. Nicotine 171-179 ATP binding cassette subfamily B member 1 Homo sapiens 135-139 16191663-4 2005 At concentrations ranging from 5 to 1000 microm, both nicotine and cotinine produced modest stimulative effects on ATPase activity in the P-gp containing membrane. Nicotine 54-62 ATP binding cassette subfamily B member 1 Homo sapiens 138-142 34522797-0 2021 The effect of CHRNA3 rs1051730 C>T and ABCB1 rs3842 A>G polymorphisms on non-small cell lung cancer and nicotine dependence in Iranian population. Nicotine 104-112 ATP binding cassette subfamily B member 1 Homo sapiens 39-44 34522797-3 2021 The objective of the current study was to investigate whether single nucleotide polymorphisms (SNPs) rs1051730C > T in CHRNA3 and rs3842A > G in ABCB1, two genes contributing in the mechanism of disposition and metabolism of nicotine and its derivatives, could modify the risk of developing lung cancer, as well as nicotine dependence in Iranian. Nicotine 225-233 ATP binding cassette subfamily B member 1 Homo sapiens 145-150 33329709-0 2020 Effects of Genetic Polymorphisms of Drug Transporter ABCB1 (MDR1) and Cytochrome P450 Enzymes CYP2A6, CYP2B6 on Nicotine Addiction and Smoking Cessation. Nicotine 112-120 ATP binding cassette subfamily B member 1 Homo sapiens 60-64