PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33329709-0	2020	Effects of Genetic Polymorphisms of Drug Transporter ABCB1 (MDR1) and Cytochrome P450 Enzymes CYP2A6, CYP2B6 on Nicotine Addiction and Smoking Cessation.	Nicotine	112-120	ATP binding cassette subfamily B member 1	Homo sapiens	53-58	
20932495-6	2011	Morphine and nicotine enhance CYP3A4 and MDR1 expression in vitro.	Nicotine	13-21	ATP binding cassette subfamily B member 1	Homo sapiens	41-45	
16191663-2	2005	Several recent studies have raised confounding results regarding the roles of P-gp in nicotine disposition.	Nicotine	86-94	ATP binding cassette subfamily B member 1	Homo sapiens	78-82	
16191663-3	2005	To ascertain this question, we examined the effects of nicotine and its major oxidative metabolite, cotinine, on ATPase activity using P-gp containing membranes, in which nicotine and cotinine-stimulated inorganic Pi was used as a marker of the binding affinity of nicotine and cotinine to P-gp.	Nicotine	171-179	ATP binding cassette subfamily B member 1	Homo sapiens	135-139	
16191663-3	2005	To ascertain this question, we examined the effects of nicotine and its major oxidative metabolite, cotinine, on ATPase activity using P-gp containing membranes, in which nicotine and cotinine-stimulated inorganic Pi was used as a marker of the binding affinity of nicotine and cotinine to P-gp.	Nicotine	171-179	ATP binding cassette subfamily B member 1	Homo sapiens	135-139	
16191663-4	2005	At concentrations ranging from 5 to 1000 microm, both nicotine and cotinine produced modest stimulative effects on ATPase activity in the P-gp containing membrane.	Nicotine	54-62	ATP binding cassette subfamily B member 1	Homo sapiens	138-142	
34522797-0	2021	The effect of CHRNA3 rs1051730 C>T and ABCB1 rs3842 A>G polymorphisms on non-small cell lung cancer and nicotine dependence in Iranian population.	Nicotine	104-112	ATP binding cassette subfamily B member 1	Homo sapiens	39-44	
34522797-3	2021	The objective of the current study was to investigate whether single nucleotide polymorphisms (SNPs) rs1051730C > T in CHRNA3 and rs3842A > G in ABCB1, two genes contributing in the mechanism of disposition and metabolism of nicotine and its derivatives, could modify the risk of developing lung cancer, as well as nicotine dependence in Iranian.	Nicotine	225-233	ATP binding cassette subfamily B member 1	Homo sapiens	145-150	
33329709-0	2020	Effects of Genetic Polymorphisms of Drug Transporter ABCB1 (MDR1) and Cytochrome P450 Enzymes CYP2A6, CYP2B6 on Nicotine Addiction and Smoking Cessation.	Nicotine	112-120	ATP binding cassette subfamily B member 1	Homo sapiens	60-64