PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28810650-0 2017 Glutathione S-transferase A1 mediates nicotine-induced lung cancer cell metastasis by promoting epithelial-mesenchymal transition. Nicotine 38-46 glutathione S-transferase alpha 1 Homo sapiens 0-28 28810650-1 2017 The present study aimed to investigate the effect of glutathione S-transferase A1 (GSTA1) on lung cancer cell viability, invasion and adhesion in the presence of nicotine in vitro. Nicotine 162-170 glutathione S-transferase alpha 1 Homo sapiens 53-81 28810650-1 2017 The present study aimed to investigate the effect of glutathione S-transferase A1 (GSTA1) on lung cancer cell viability, invasion and adhesion in the presence of nicotine in vitro. Nicotine 162-170 glutathione S-transferase alpha 1 Homo sapiens 83-88 28810650-7 2017 The current study indicated that the expression of GSTA1 was increased in A549 cells following nicotine treatment. Nicotine 95-103 glutathione S-transferase alpha 1 Homo sapiens 51-56 28810650-9 2017 In addition, the increase in lung cancer cell viability, invasion and adhesion by nicotine was suppressed following GSTA1 knockdown. Nicotine 82-90 glutathione S-transferase alpha 1 Homo sapiens 116-121 28810650-10 2017 Furthermore, GSTA1 affected the expression of EMT markers in nicotine-treated or untreated lung cancer cells. Nicotine 61-69 glutathione S-transferase alpha 1 Homo sapiens 13-18 28810650-11 2017 Thus the present study demonstrates that GSTA1 promotes lung cancer cell invasion and adhesion and mediates the effect of nicotine on lung cancer cell metastasis in vitro. Nicotine 122-130 glutathione S-transferase alpha 1 Homo sapiens 41-46